4.8 Article

Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT1

Related references

Note: Only part of the references are listed.
Review Biotechnology & Applied Microbiology

Are sirtuins viable targets for improving healthspan and lifespan?

Joseph A. Baur et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Article Chemistry, Medicinal

SIRT1 Modulation as a Novel Approach to the Treatment of Diseases of Aging

Charles A. Blum et al.

JOURNAL OF MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen (R) technology

Matthew B. Robers et al.

MOLECULAR BIOSYSTEMS (2011)

Article Multidisciplinary Sciences

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Camilla Burnett et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

SIRT1 Activation by Small Molecules KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR

Han Dai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Cell Biology

Mammalian circadian clock and metabolism - the epigenetic link

Marina Maria Bellet et al.

JOURNAL OF CELL SCIENCE (2010)

Article Medicine, Research & Experimental

Sirt1 activation protects the mouse renal medulla from oxidative injury

Wenjuan He et al.

JOURNAL OF CLINICAL INVESTIGATION (2010)

Article Neurosciences

Plasticity and specificity of the circadian epigenome

Selma Masri et al.

NATURE NEUROSCIENCE (2010)

Review Pharmacology & Pharmacy

Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases

Shin-ichiro Imai et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2010)

Article Multidisciplinary Sciences

Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1

Yasukazu Nakahata et al.

SCIENCE (2009)

Article Multidisciplinary Sciences

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD(+) Biosynthesis

Kathryn Moynihan Ramsey et al.

SCIENCE (2009)

Review Oncology

Metabolism and cancer: the circadian clock connection

Saurabh Sahar et al.

NATURE REVIEWS CANCER (2009)

Article Biochemistry & Molecular Biology

SIRT1 regulates circadian clock gene expression through PER2 deacetylation

Gad Asher et al.

Article Multidisciplinary Sciences

Sirt1 protects against high-fat diet-induced metabolic damage

Paul T. Pfluger et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

CLOCK-mediated acetylation of BMAL1 controls circadian function

Jun Hirayama et al.

NATURE (2007)

Article Cell Biology

SIRT1 transgenic mice show phenotypes resembling calorie restriction

Laura Bordone et al.

AGING CELL (2007)

Article Multidisciplinary Sciences

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Jill C. Milne et al.

NATURE (2007)

Article Multidisciplinary Sciences

Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation

Brooke H. Miller et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Circadian orchestration of the hepatic Proteome

Akhilesh B. Reddy et al.

CURRENT BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Circadian regulator CLOCK is a histone acetyltransferase

Masao Doi et al.

Article Multidisciplinary Sciences

Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1

I Yujnovsky et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Circadian clock control by SUMOylation of BMAL1

L Cardone et al.

SCIENCE (2005)

Article Multidisciplinary Sciences

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

HL Cheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

KT Howitz et al.

NATURE (2003)

Article Biochemical Research Methods

LC/MS analysis of NAD biosynthesis using stable isotope pyridine precursors

J Evans et al.

ANALYTICAL BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Coordinated transcription of key pathways in the mouse by the circadian clock

S Panda et al.

Review Physiology

Molecular analysis of mammalian circadian rhythms

SM Reppert et al.

ANNUAL REVIEW OF PHYSIOLOGY (2001)

Review Food Science & Technology

A comprehensive overview of the complex relationship between epigenetics, bioactive components, cancer, and aging

Sule Kocabas et al.

Summary: Epigenetic modifications, nutritional components, and their impact on gene expression play crucial roles in cancer and aging, which can be altered by adjusting dietary habits.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION