Related references
Note: Only part of the references are listed.Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ
Kyeung Min Joo et al.
CELL REPORTS (2013)
Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma
Paolo P. Provenzano et al.
CANCER CELL (2012)
mTOR activates hypoxia-inducible factor-1α and inhibits neuronal apoptosis in the developing rat brain during the early phase after hypoxia-ischemia
Hongju Chen et al.
NEUROSCIENCE LETTERS (2012)
Initial testing (stage 1) of the mTOR kinase inhibitor AZD8055 by the pediatric preclinical testing program
Peter J. Houghton et al.
PEDIATRIC BLOOD & CANCER (2012)
Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells
Qihui Shi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Computational Approaches for Analyzing Information Flow in Biological Networks
Boris Kholodenko et al.
SCIENCE SIGNALING (2012)
Chronic Activation of mTOR Complex 1 Is Sufficient to Cause Hepatocellular Carcinoma in Mice
Suchithra Menon et al.
SCIENCE SIGNALING (2012)
A clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells
Chao Ma et al.
NATURE MEDICINE (2011)
Oxygen Sensing, Homeostasis, and Disease
David De Bels et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
NORMALIZATION OF THE VASCULATURE FOR TREATMENT OF CANCER AND OTHER DISEASES
Shom Goel et al.
PHYSIOLOGICAL REVIEWS (2011)
Oncogenic EGFR Signaling Activates an mTORC2-NF-κB Pathway That Promotes Chemotherapy Resistance
Kazuhiro Tanaka et al.
CANCER DISCOVERY (2011)
MECHANISMS OF DISEASE Oxygen Sensing, Homeostasis, and Disease
Gregg L. Semenza
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres
Eli E. Bar et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Chemistries for Patterning Robust DNA MicroBarcodes Enable Multiplex Assays of Cytoplasm Proteins from Single Cancer Cells
Young Shik Shin et al.
CHEMPHYSCHEM (2010)
mTOR signaling in glioblastoma: lessons learned from bench to bedside
David Akhavan et al.
NEURO-ONCOLOGY (2010)
Negative feedback control of HIF-1 through REDD1-regulated ROS suppresses tumorigenesis
Peter Horak et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Pharmacology of mTOR Inhibition
David A. Guertin et al.
SCIENCE SIGNALING (2009)
Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
Maurice Phillip DeYoung et al.
GENES & DEVELOPMENT (2008)
Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases
Beth Apsel et al.
NATURE CHEMICAL BIOLOGY (2008)
Antitumor activity of rapamycin in a phase I trial for patients with recurrent PTEN-Deficient glioblastoma
Tim F. Cloughesy et al.
PLOS MEDICINE (2008)
HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer
Jessica A. Bertout et al.
NATURE REVIEWS CANCER (2008)
Hypoxia signalling through mTOR and the unfolded protein response in cancer
Bradly G. Wouters et al.
NATURE REVIEWS CANCER (2008)
Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with rheb
Yong Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
DNA-encoded antibody libraries: A unified platform for multiplexed cell sorting and detection of genes and proteins
Ryan C. Bailey et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-Deficient and PTEN-intact glioblastoma cells
Maria Y. Wang et al.
CANCER RESEARCH (2006)
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
Qi-Wen Fan et al.
CANCER CELL (2006)
Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response
JN Sarkaria et al.
CLINICAL CANCER RESEARCH (2006)
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
SM Chang et al.
INVESTIGATIONAL NEW DRUGS (2005)
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways
PK Majumder et al.
NATURE MEDICINE (2004)
Exploiting tumour hypoxia in cancer treatment
JM Brown et al.
NATURE REVIEWS CANCER (2004)
Hypoxia - A key regulatory factor in tumour growth
AL Harris
NATURE REVIEWS CANCER (2002)
From micro- to nanofabrication with soft materials
SR Quake et al.
SCIENCE (2000)