Related references
Note: Only part of the references are listed.Cullin-RING Ligases as Attractive Anti-cancer Targets
Yongchao Zhao et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression
Achim Werner et al.
NATURE CELL BIOLOGY (2013)
Elevated Expression of Fn14 in Non-Small Cell Lung Cancer Correlates with Activated EGFR and Promotes Tumor Cell Migration and Invasion
Timothy G. Whitsett et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation
Chie Kanei-Ishii et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Downregulation of Polo-Like Kinase 4 in Hepatocellular Carcinoma Associates with Poor Prognosis
Lili Liu et al.
PLOS ONE (2012)
The intracellular stability of DLC1 is regulated by the 26S proteasome in human hepatocellular carcinoma cell line Hep3B
Hong-wei Luo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Rho GTPase Effector Functions in Tumor Cell Invasion and Metastasis
Somesh Baranwal et al.
CURRENT DRUG TARGETS (2011)
Implication of Rho GTPases in Neurodegenerative Diseases
Judith Antoine-Bertrand et al.
CURRENT DRUG TARGETS (2011)
X-Linked Mental Retardation Gene CUL4B Targets Ubiquitylation of H3K4 Methyltransferase Component WDR5 and Regulates Neuronal Gene Expression
Tadashi Nakagawa et al.
MOLECULAR CELL (2011)
The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
Anja Puklowski et al.
NATURE CELL BIOLOGY (2011)
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis
Colin R. Lindsay et al.
NATURE COMMUNICATIONS (2011)
Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?
Dominico Vigil et al.
NATURE REVIEWS CANCER (2010)
Proliferation defects and genome instability in cells lacking Cul4A
D. Kopanja et al.
ONCOGENE (2009)
CRL4s: the CUL4-RING E3 ubiquitin ligases
Sarah Jackson et al.
TRENDS IN BIOCHEMICAL SCIENCES (2009)
WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase
Jian Hu et al.
GENES & DEVELOPMENT (2008)
DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma
Wen Xue et al.
GENES & DEVELOPMENT (2008)
Effects of Structure of Rho GTPase-activating Protein DLC-1 on Cell Morphology and Migration
Tai Young Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development
Chad M. McCall et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms
Kevin D. Healy et al.
MOLECULAR CARCINOGENESIS (2008)
VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation
J. Huang et al.
ONCOGENE (2008)
Deleted in Liver Cancer 1 (DLC1) Negatively Regulates Rho/ROCK/MLC Pathway in Hepatocellular Carcinoma
Carmen Chak-Lui Wong et al.
PLOS ONE (2008)
SnapShot: Rho family GTPases
Francisco M. Vega et al.
CELL (2007)
GEFs and GAPs: Critical elements in the control of small G proteins
Johannes L. Bos et al.
CELL (2007)
Aberrant methylation of the 8p22 tumor suppressor gene DLC1 in renal cell carcinoma
Qlan Zhang et al.
CANCER LETTERS (2007)
The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation
T. J. Seng et al.
ONCOGENE (2007)
DLC-1: a Rho GTPase-activating protein and tumour suppressor
Marian E. Durkin et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2007)
DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases
Yizhou Joseph He et al.
GENES & DEVELOPMENT (2006)
Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer:: Potential clinical applications
M Guan et al.
CLINICAL CANCER RESEARCH (2006)
DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas
BZ Yuan et al.
ONCOGENE (2004)
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
TY Kim et al.
ONCOGENE (2003)
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers
BZ Yuan et al.
CANCER GENETICS AND CYTOGENETICS (2003)
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
A Bhattacharjee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)