Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 109, Issue 10, Pages 3979-3984Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1200506109
Keywords
functional MRI; resting state; intrinsic activity; connectivity; spontaneous fluctuation
Categories
Funding
- National Institute on Drug Abuse, National Institutes of Health
- National Institute of Neurological Disorders and Stroke [NS06833]
- China's National Strategic Basic Research Program (973) [2012CB720700]
Ask authors/readers for more resources
The default mode network (DMN) in humans has been suggested to support a variety of cognitive functions and has been implicated in an array of neuropsychological disorders. However, its function (s) remains poorly understood. We show that rats possess a DMN that is broadly similar to the DMNs of nonhuman primates and humans. Our data suggest that, despite the distinct evolutionary paths between rodent and primate brain, a well-organized, intrinsically coherent DMN appears to be a fundamental feature in the mammalian brain whose primary functions might be to integrate multimodal sensory and affective information to guide behavior in anticipation of changing environmental contingencies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available