4.8 Article

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Structure-Based Discovery of a Novel Inhibitor Targeting the β-Catenin/Tcf4 Interaction

Wang Tian et al.

BIOCHEMISTRY (2012)

Review Biochemistry & Molecular Biology

Wnt/β-Catenin Signaling and Disease

Hans Clevers et al.

Article Chemistry, Multidisciplinary

Structure of the Stapled p53 Peptide Bound to Mdm2

Sohee Baek et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)

Article Biochemical Research Methods

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

Young-Woo Kim et al.

NATURE PROTOCOLS (2011)

Review Oncology

Targeting cancer stem cells by inhibiting Wnt, notch, and Hedgehog pathways

Naoko Takebe et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2011)

Article Multidisciplinary Sciences

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

Desheng Lu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway

Foster C. Gonsalves et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Oncology

A Stapled p53 Helix Overcomes HDMX-Mediated Suppression of p53

Federico Bernal et al.

CANCER CELL (2010)

Article Biochemistry & Molecular Biology

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

Curtis A. Thorne et al.

NATURE CHEMICAL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

Michelle L. Stewart et al.

NATURE CHEMICAL BIOLOGY (2010)

Article Multidisciplinary Sciences

Hydrocarbon double-stapling remedies the proteolytic instability of a lengthy peptide therapeutic

Gregory H. Bird et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

Shih-Min A. Huang et al.

NATURE (2009)

Article Multidisciplinary Sciences

Direct inhibition of the NOTCH transcription factor complex

Raymond E. Moellering et al.

NATURE (2009)

Article Biochemistry & Molecular Biology

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

Baozhi Chen et al.

NATURE CHEMICAL BIOLOGY (2009)

Review Pharmacology & Pharmacy

Predicting cell-penetrating peptides

Mats Hansen et al.

ADVANCED DRUG DELIVERY REVIEWS (2008)

Article Biochemistry & Molecular Biology

Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid

Shibani Bhattacharya et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

BAX activation is initiated at a novel interaction site

Evripidis Gavathiotis et al.

NATURE (2008)

Article Biochemistry & Molecular Biology

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Nika N. Danial et al.

NATURE MEDICINE (2008)

Article Chemistry, Multidisciplinary

Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide

Federico Bernal et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)

Article Biochemistry & Molecular Biology

Crystal structure of a β-catenin/BCL9/Tcf4 complex

James Sampietro et al.

MOLECULAR CELL (2006)

Article Biochemistry & Molecular Biology

Identification of a specific inhibitor of the dishevelled PDZ domain

JF Shan et al.

BIOCHEMISTRY (2005)

Article Multidisciplinary Sciences

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

LD Walensky et al.

SCIENCE (2004)

Article Multidisciplinary Sciences

A small molecule inhibitor of β-catenin/cyclic AMP response element-binding protein transcription

KH Emami et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

M van de Wetering et al.

Article Medicine, General & Internal

Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis

NS Fearnhead et al.

BRITISH MEDICAL BULLETIN (2002)

Article Biochemistry & Molecular Biology

Crystal structure of a β-catenin/Tcf complex

TA Graham et al.

Article Chemistry, Multidisciplinary

An all-hydrocarbon cross-linking system for enhancing the helicity and metabolic stability of peptides

CE Schafmeister et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)