4.8 Article

Ligand binding to protein-binding pockets with wet and dry regions

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Understanding Kinase Selectivity Through Energetic Analysis of Binding Site Waters

Daniel D. Robinson et al.

CHEMMEDCHEM (2010)

Article Biochemistry & Molecular Biology

Computational evaluation of protein-small molecule binding

Olgun Guvench et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

Article Chemistry, Physical

Prediction of the Water Content in Protein Binding Sites

Julien Michel et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2009)

Article Biochemistry & Molecular Biology

High-energy water sites determine peptide binding affinity and specificity of PDZ domains

Thijs Beuming et al.

PROTEIN SCIENCE (2009)

Review Biochemistry & Molecular Biology

Binding of Small-Molecule Ligands to Proteins: What You See Is Not Always What You Get

David L. Mobley et al.

STRUCTURE (2009)

Article Chemistry, Multidisciplinary

Role of the active-site solvent in the thermodynamics of factor Xa ligand binding

Robert Abel et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)

Review Pharmacology & Pharmacy

Water, water everywhere - except where it matters?

Steve W. Homans

DRUG DISCOVERY TODAY (2007)

Article Multidisciplinary Sciences

Motifs for molecular recognition exploiting hydrophobic enclosure in protein-ligand binding

Tom Young et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Chemistry, Medicinal

Extra precision glide: Docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes

Richard A. Friesner et al.

JOURNAL OF MEDICINAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Structural evidence for adaptive ligand binding of glycolipid transfer protein

TT Airenne et al.

JOURNAL OF MOLECULAR BIOLOGY (2006)

Article Chemistry, Multidisciplinary

Strong solute-solute dispersive interactions in a protein-ligand complex

R Malham et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Chemistry, Multidisciplinary

Van der waals interactions dominate ligand-protein association in a protein binding site occluded from solvent water

E Barratt et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Biochemistry & Molecular Biology

Structure and biochemical analysis of a secretin pilot protein

PI Lario et al.

EMBO JOURNAL (2005)

Article Chemistry, Multidisciplinary

Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2-methoxy-3-isobutylpyrazine to the major urinary protein

RJ Bingham et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)

Article Biochemistry & Molecular Biology

Hydrophobicity maps of the N-peptide coiled coil of HIV-1 gp41

X Siebert et al.

BIOCHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Structural basis of pheromone binding to mouse major urinary protein (MUP-I)

DE Timm et al.

PROTEIN SCIENCE (2001)