Related references
Note: Only part of the references are listed.Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1
Katrin Duevel et al.
MOLECULAR CELL (2010)
COSMIC (the Catalogue of Somatic Mutations in Cancer): a resource to investigate acquired mutations in human cancer
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2010)
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
Ryan J. O. Dowling et al.
SCIENCE (2010)
Inhibitor hijacking of Akt activation
Tatsuya Okuzumi et al.
NATURE CHEMICAL BIOLOGY (2009)
CCL2 Is a Negative Regulator of AMP-Activated Protein Kinase to Sustain mTOR Complex-1 Activation, Survivin Expression, and Cell Survival in Human Prostate Cancer PC3 Cells
Hernan Roca et al.
NEOPLASIA (2009)
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
Dolores Hambardzumyan et al.
GENES & DEVELOPMENT (2008)
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation
Wei Guo et al.
NATURE (2008)
Expansion and evolution of cell death programmes
Alexei Degterev et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
The role of PTEN signaling perturbations in cancer and in targeted therapy
M. Keniry et al.
ONCOGENE (2008)
S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
N. Valerio Dorrello et al.
SCIENCE (2006)
The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice
Mei-Ling Chen et al.
GENES & DEVELOPMENT (2006)
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Omer H. Yilmaz et al.
NATURE (2006)
Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation
SY Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
MK Holz et al.
CELL (2005)
Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases
B Raught et al.
EMBO JOURNAL (2004)
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
SH Um et al.
NATURE (2004)
Somatic inactivation of Nfl in hematopoietic cells results in a progressive myeloproliferative disorder
DT Le et al.
BLOOD (2004)
The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor
CJ Fox et al.
GENES & DEVELOPMENT (2003)
Akt activation promotes degradation of tuberin and FOXO3a via the proteasome
DR Plas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factors
PO Schnell et al.
JOURNAL OF NEUROCHEMISTRY (2003)
IL-7 enhances the survival and maintains the size of naive T cells
JC Rathmell et al.
JOURNAL OF IMMUNOLOGY (2001)
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
N Masson et al.
EMBO JOURNAL (2001)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
WX Zong et al.
GENES & DEVELOPMENT (2001)
Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane
MGV Heiden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
K Gottlob et al.
GENES & DEVELOPMENT (2001)
Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology
DR Plas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
