Related references
Note: Only part of the references are listed.Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo
Olivier Delelis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2010)
Strand transfer inhibitors of HIV-1 integrase: Bringing IN new era of antiretroviral therapy
Damian J. McColl et al.
ANTIVIRAL RESEARCH (2010)
A Dynamic Model of HIV Integrase Inhibition and Drug Resistance
Alex L. Perryman et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Retroviral intasome assembly and inhibition of DNA strand transfer
Stephen Hare et al.
NATURE (2010)
Molecular Architecture of the Mos1 Paired-End Complex: The Structural Basis of DNA Transposition in a Eukaryote
Julia M. Richardson et al.
CELL (2009)
Induced-Fit Docking Approach Provides Insight into the Binding Mode and Mechanism of Action of HIV-1 Integrase Inhibitors
Maria Letizia Barreca et al.
CHEMMEDCHEM (2009)
Structural basis for HIV-1 DNA integration in the human genome, role of the LEDGF/P75 cofactor
Fabrice Michel et al.
EMBO JOURNAL (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways
Signe Fransen et al.
JOURNAL OF VIROLOGY (2009)
The G140S mutation in HIV integrases from raltegravir-resistant patients rescues catalytic defect due to the resistance Q148H mutation
Olivier Delelis et al.
NUCLEIC ACIDS RESEARCH (2009)
Functional and structural characterization of the integrase from the prototype foamy virus
Eugene Valkov et al.
NUCLEIC ACIDS RESEARCH (2009)
Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase α4 helix
Zeina Hobaika et al.
NUCLEIC ACIDS RESEARCH (2009)
Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs
Akram Alian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structural Basis for Functional Tetramerization of Lentiviral Integrase
Stephen Hare et al.
PLOS PATHOGENS (2009)
Selection of diverse and clinically relevant integrase inhibitor-resistant human immunodeficiency virus type 1 mutants
Masanori Kobayashi et al.
ANTIVIRAL RESEARCH (2008)
The Terminal (Catalytic) Adenosine of the HIV LTR Controls the Kinetics of Binding and Dissociation of HIV Integrase Strand Transfer Inhibitors
David R. Langley et al.
BIOCHEMISTRY (2008)
Discovery of Raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection
Vincenzo Summa et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Modeling, analysis, and validation of a novel HIV integrase structure provide insights into the binding modes of potent integrase inhibitors
X. Chen et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Subunit-specific protein footprinting reveals significant structural Rearrangements and a role for N-terminal Lys-14 of HIV-1 integrase during viral DNA binding
Zhuojun Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Broad Antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137)
Kazuya Shimura et al.
JOURNAL OF VIROLOGY (2008)
Inhibition of human immunodeficiency virus type I concerted integration by strand transfer inhibitors which recognize a transient structural intermediate
Krishan K. Pandey et al.
JOURNAL OF VIROLOGY (2007)
Loop202-208 in avian sarcoma virus integrase mediates tetramer assembly and processing activity
Mary A. Bosserman et al.
BIOCHEMISTRY (2007)
In-Silico docking of HIV-1 integrase inhibitors reveals a novel drug type acting on an enzyme/DNA reaction intermediate
Andrea Savarino
RETROVIROLOGY (2007)
Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity
Elvire Guiot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Retroviral DNA integration: reaction pathway and critical intermediates
M Li et al.
EMBO JOURNAL (2006)
Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat ends
AP Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Integration requires a specific interaction of the donor DNA terminal 5′-cytosine with glutamine 148 of the HIV-1 integrase flexible loop
AA Johnson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Crystal structures of RNase H bound to an RNA/DNA hybrid: Substrate specificity and metal-dependent catalysis
M Nowotny et al.
CELL (2005)
A three-dimensional model of the human immunodeficiency virus type 1 integration complex
J Wielens et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2005)
HIV-1 integrase crosslinked oligomers are active in vitro
A Faure et al.
NUCLEIC ACIDS RESEARCH (2005)
Diketo acid inhibitor mechanism and HIV-1 integrase: Implications for metal binding in the active site of phosphotransferase enzymes
JA Grobler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein
JY Wang et al.
EMBO JOURNAL (2001)
Asymmetric processing of human immunodeficiency virus type 1 cDNA in vivo: Implications for functional end coupling during the chemical steps of DNA transposition
HM Chen et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes
K Gao et al.
EMBO JOURNAL (2001)
HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase
AS Espeseth et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding
JCH Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Three-dimensional structure of the Tn5 synaptic complex transposition intermediate
DR Davies et al.
SCIENCE (2000)
Evolution of the gypsy endogenous retrovirus in the Drosophila melanogaster subgroup
C Terzian et al.
MOLECULAR BIOLOGY AND EVOLUTION (2000)
X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293) - An initial glance of the viral DNA binding platform
ZG Chen et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase
ZN Yang et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Share Paper
