Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 107, Issue 45, Pages 19163-19166Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.1006888107
Keywords
electrocoalescence; high-throughput biology; in vitro compartmentalization
Categories
Funding
- Massachusetts Life Sciences Center
- National Science Foundation [DMR-1006546]
- Harvard Materials Research Science and Engineering Centers [DMR-0820484]
- Saint-Gobain Recherche
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [820484] Funding Source: National Science Foundation
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Adding reagents to drops is one of the most important functions in droplet-based microfluidic systems; however, a robust technique to accomplish this does not exist. Here, we introduce the picoinjector, a robust device to add controlled volumes of reagent using electro-microfluidics at kilohertz rates. It can also perform multiple injections for serial and combinatorial additions.
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