4.8 Article

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension

Related references

Note: Only part of the references are listed.
Article Medicine, Research & Experimental

Role of the WNK-activated SPAK kinase in regulating blood pressure

Fatema H. Rafiqi et al.

EMBO MOLECULAR MEDICINE (2010)

Review Peripheral Vascular Disease

Thiazide Effects and Adverse Effects Insights From Molecular Genetics

David H. Ellison et al.

HYPERTENSION (2009)

Article Biochemistry & Molecular Biology

Regulation of ROMK Channel and K+ Homeostasis by Kidney-specific WNK1 Kinase

Zhen Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

WNK4 Diverts the Thiazide-sensitive NaCl Cotransporter to the Lysosome and Stimulates AP-3 Interaction

Arohan R. Subramanya et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Peripheral Vascular Disease

WNK kinases and renal sodium transport in health and disease - An integrated view

James A. McCormick et al.

HYPERTENSION (2008)

Article Endocrinology & Metabolism

A novel protein kinase signaling pathway essential for blood pressure regulation in humans

Kristopher T. Kahle et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2008)

Article Biochemistry & Molecular Biology

Defective ENaC processing and function in tissue kallikrein-deficient mice

Nicolas Picard et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Medicine, Research & Experimental

The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex

Chao-Ling Yang et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Article Multidisciplinary Sciences

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo

Aaron M. Ring et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Urology & Nephrology

WNK1 affects surface expression of the ROMK potassium channel independent of WNK4

Georgina Cope et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

Article Multidisciplinary Sciences

WNK1 kinase isoform switch regulates renal potassium excretion

James B. Wade et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Physiology

Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform

AR Subramanya et al.

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2006)

Article Multidisciplinary Sciences

Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms

A Lazrak et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis

J Rinehart et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Medicine, General & Internal

WNK4 regulates airway Na+ transport:: study of familial hyperkalaemia and hypertension

Z Farfel et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Medicine, Research & Experimental

Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport

CL Yang et al.

JOURNAL OF CLINICAL INVESTIGATION (2005)

Article Urology & Nephrology

Altered renal distal tubule structure and renal Na+ and Ca2+ handling in a mouse model for Gitelman's syndrome

J Loffing et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2004)

Article Genetics & Heredity

WNK4 regulates the balance between renal NaCl reabsorption and K+ secretion

KT Kahle et al.

NATURE GENETICS (2003)

Article Biochemistry & Molecular Biology

Multiple promoters in the WNK1 gene: One controls expression of a kidney-specific kinase-defective isoform

C Delaloy et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Biochemistry & Molecular Biology

Maturation of the epithelial Na+ channel involves proteolytic processing of the α- and γ-subunits

RP Hughey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4

FH Wilson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Human hypertension caused by mutations in WNK kinases

FH Wilson et al.

SCIENCE (2001)

Article Biochemistry & Molecular Biology

WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II

BE Xu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Letter Genetics & Heredity

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

CI Rodríguez et al.

NATURE GENETICS (2000)