Related references
Note: Only part of the references are listed.Drug-target identification from total cellular lysate by drug-induced conformational changes
Yoichi Nishiya et al.
ANALYTICAL BIOCHEMISTRY (2009)
Identifying the proteins to which small-molecule probes and drugs bind in cells
Shao-En Ong et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Activity-based protein profiling: From enzyme chemistry
Benjamin F. Cravatt et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
FoxO transcription factors in the maintenance of cellular homeostasis during aging
Dervis A. M. Salih et al.
CURRENT OPINION IN CELL BIOLOGY (2008)
Proteomic methods for drug target discovery
Lekha Sleno et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2008)
Quantitative evidence for conserved longevity pathways between divergent eukaryotic species
Erica D. Smith et al.
GENOME RESEARCH (2008)
Label-free detection of differential protein expression by LC/MALDI mass spectrometry
Hendrik Neubert et al.
JOURNAL OF PROTEOME RESEARCH (2008)
A Biomedically Enriched Collection of 7000 Human ORF Clones
Andreas Rolfs et al.
PLOS ONE (2008)
Drug target identification using side-effect similarity
Monica Campillos et al.
SCIENCE (2008)
Target deconvolution strategies in drug discovery
Georg C. Terstappen et al.
NATURE REVIEWS DRUG DISCOVERY (2007)
High-throughput screening assays for the identification of chemical probes
James Inglese et al.
NATURE CHEMICAL BIOLOGY (2007)
Energetics-based protein profiling on a proteomic scale: Identification of proteins resistant to proteolysis
Chiwook Park et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
Malene Hansen et al.
AGING CELL (2007)
Yeast Genomics and drug target identification
Nike Bharucha et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2007)
The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
Justin Lamb et al.
SCIENCE (2006)
A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules
Laura A. Banaszynski et al.
CELL (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway
RA Butcher et al.
NATURE CHEMICAL BIOLOGY (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation
ME Bordeleau et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Substrate-specific activation of sirtuins by resveratrol
M Kaeberlein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding
CW Park et al.
NATURE METHODS (2005)
A genome-wide overexpression screen in yeast for small-molecule target identification
H Luesch et al.
CHEMISTRY & BIOLOGY (2005)
Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes
PY Lum et al.
CELL (2004)
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
JG Wood et al.
NATURE (2004)
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets
US Eggert et al.
PLOS BIOLOGY (2004)
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips
J Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Multidimensional drug profiling by automated microscopy
ZE Perlman et al.
SCIENCE (2004)
Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
AB Parsons et al.
NATURE BIOTECHNOLOGY (2004)
Target identification in chemical genetics: The (often) missing link
L Burdine et al.
CHEMISTRY & BIOLOGY (2004)
The TOR pathway: A target for cancer therapy
MA Bjornsti et al.
NATURE REVIEWS CANCER (2004)
Global analysis of protein expression in yeast
S Ghaemmaghami et al.
NATURE (2003)
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
KT Howitz et al.
NATURE (2003)
Conditional protein alleles using knockin mice and a chemical inducer of dimerization
K Stankunas et al.
MOLECULAR CELL (2003)
An automated multidimensional protein identification technology for shotgun proteomics
DA Wolters et al.
ANALYTICAL CHEMISTRY (2001)
A yeast sensor of ligand binding
CL Tucker et al.
NATURE BIOTECHNOLOGY (2001)
The human estrogen receptor-α is a ubiquitinated protein whose stability is affected differentially by agonists, antagonists, and selective estrogen receptor modulators
AL Wijayaratne et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Global analysis of protein activities using proteome chips
H Zhu et al.
SCIENCE (2001)
Functional discovery via a compendium of expression profiles
TR Hughes et al.
CELL (2000)
Share Paper
