Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 106, Issue 42, Pages 18034-18039Publisher
NATL ACAD SCIENCES
DOI: 10.1073/pnas.0810943106
Keywords
column; cone; functional MRI; functional architecture; primate
Categories
Funding
- Alexander von Humboldt Foundation
- German Ministry of Science [01GO0506]
- Neuroscience Program
- Wellesley College
- Whitehall Foundation
- Direct For Biological Sciences
- Division Of Integrative Organismal Systems [0918064] Funding Source: National Science Foundation
Ask authors/readers for more resources
Large islands of extrastriate cortex that are enriched for color-tuned neurons have recently been described in alert macaque using a combination of functional magnetic resonance imaging (fMRI) and single-unit recording. These millimeter-sized islands, dubbed globs,'' are scattered throughout the posterior inferior temporal cortex (PIT), a swath of brain anterior to area V3, including areas V4, PITd, and posterior TEO. We investigated the micro-organization of neurons within the globs. We used fMRI to identify the globs and then used MRI-guided microelectrodes to test the color properties of single glob cells. We used color stimuli that sample the CIELUV perceptual color space at regular intervals to test the color tuning of single units, and make two observations. First, color-tuned neurons of various color preferences were found within single globs. Second, adjacent glob cells tended to have the same color tuning, demonstrating that glob cells are clustered by color preference and suggesting that they are arranged in color columns. Neurons separated by 50 mu m, measured parallel to the cortical sheet, had more similar color tuning than neurons separated by 100 mu m, suggesting that the scale of the color columns is < 100 mu m. These results show that color-tuned neurons in PIT are organized by color preference on a finer scale than the scale of single globs. Moreover, the color preferences of neurons recorded sequentially along a given electrode penetration shifted gradually in many penetrations, suggesting that the color columns are arranged according to a chromotopic map reflecting perceptual color space.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available