Related references
Note: Only part of the references are listed.The annealing helicase HARP protects stalled replication forks
Jingsong Yuan et al.
GENES & DEVELOPMENT (2009)
TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forks
Shan Yan et al.
JOURNAL OF CELL BIOLOGY (2009)
Polo-Like Kinase 1 Depletion Induces DNA Damage in Early S Prior to Caspase Activation
Hyungshin Yim et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability
Renee D. Paulsen et al.
MOLECULAR CELL (2009)
Plx1 is required for chromosomal DNA replication under stressful conditions
Kristina Trenz et al.
EMBO JOURNAL (2008)
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
Daniel A. Mordes et al.
GENES & DEVELOPMENT (2008)
ATR: an essential regulator of genome integrity
Karlene A. Cimprich et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
An oncogene-induced DNA damage model for cancer development
Thanos D. Halazonetis et al.
SCIENCE (2008)
Recurrent gene fusions in prostate cancer
Chandan Kumar-Sinha et al.
NATURE REVIEWS CANCER (2008)
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination
David Alvaro et al.
PLOS GENETICS (2007)
The genomic landscapes of human breast and colorectal cancers
Laura D. Wood et al.
SCIENCE (2007)
The Rad9-Hus1-Rad1 checkpoint interaction of TopBP1 with ATR
Joon Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Cyclin-dependent kinase 2-dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage
Jeremy S. Myers et al.
CANCER RESEARCH (2007)
Phosphorylation of ATR-interacting protein on Ser139 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function
Monica Venere et al.
CANCER RESEARCH (2007)
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
Sinny Delacroix et al.
GENES & DEVELOPMENT (2007)
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs
Charles Swanton et al.
CANCER CELL (2007)
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
Shuhei Matsuoka et al.
SCIENCE (2007)
Function of a conserved checkpoint recruitment domain in ATRIP proteins
Heather L. Ball et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
A role for the HOXB7 homeodomain protein in DNA repair
Ethel Rubin et al.
CANCER RESEARCH (2007)
The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
Frederick A. Mallette et al.
GENES & DEVELOPMENT (2007)
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints
Jirina Bartkova et al.
NATURE (2006)
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
Raffaella Di Micco et al.
NATURE (2006)
The consensus coding sequences of human breast and colorectal cancers
Tobias Sjoeblom et al.
SCIENCE (2006)
Lessons from Nature: microRNA-based shRNA libraries
Kenneth Chang et al.
NATURE METHODS (2006)
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM and KAP-1 dependent pathway
Yael Ziv et al.
NATURE CELL BIOLOGY (2006)
TopBP1 activates the ATR-ATRIP complex
A Kumagai et al.
CELL (2006)
Overexpression of polo-like kinase 1 (PLK1) and chromosomal instability in bladder cancer
Yoshiaki Yamamoto et al.
ONCOLOGY (2006)
Dimerization of the ATRIP protein through the coiled-coil motif and its implication to the maintenance of stalled replication forks
E Itakura et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
ATRIP oligomerization is required for ATR-dependent checkpoint signaling
HL Ball et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage
RG Syljuåsen et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation
HL Ball et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
NATURE (2005)
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
VG Gorgoulis et al.
NATURE (2005)
Chk1 activation requires Rad9 S/TQ-site phosphorylation to promote association with C-terminal BCRT domains of Rad4TOPBP1
K Furuya et al.
GENES & DEVELOPMENT (2004)
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
L Zou et al.
SCIENCE (2003)
ATM and related protein kinases: Safeguarding genome integrity
Y Shiloh
NATURE REVIEWS CANCER (2003)
ATR regulates fragile site stability
AM Casper et al.
CELL (2002)
ATR and ATRIP: Partners in checkpoint signaling
D Cortez et al.
SCIENCE (2001)
Share Paper
