Related references
Note: Only part of the references are listed.Autophagy in the pathogenesis of disease
Beth Levine et al.
CELL (2008)
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
Paul Tannous et al.
CIRCULATION (2008)
Mechanisms of disease: Cardiac plasticity
Joseph A. Hill et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Myocyte autophagy in heart disease - Friend or foe?
Beverly A. Rothermel et al.
AUTOPHAGY (2007)
Human αB-crystallin mutation causes oxido-reductive stress and protein aggregation cardiomyopathy in mice
Namakkal S. Rajasekaran et al.
CELL (2007)
Cardiac autophagy is a maladaptive response to hemodynamic stress
Hongxin Zhu et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Distinct roles of autophagy in the heart during ischemia and reperfusion - Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
Yutaka Matsui et al.
CIRCULATION RESEARCH (2007)
The roles of intracellular protein-degradation pathways in neurodegeneration
David C. Rubinsztein
NATURE (2006)
Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis
Shida Yousefi et al.
NATURE CELL BIOLOGY (2006)
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
Taichi Hara et al.
NATURE (2006)
Loss of autophagy in the central nervous system causes neurodegeneration in mice
Masaaki Komatsu et al.
NATURE (2006)
Aberrant protein aggregation is essential for a mutant desmin to impair the proteolytic function of the ubiquitin-proteasome system in cardiomyocytes
JB Liu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2006)
Aggregate-prone proteins are cleared from the cytosol by autophagy: Therapeutic implications
Andrea Williams et al.
CURRENT TOPICS IN DEVELOPMENTAL BIOLOGY, VOL 76 (2006)
Mitochondrial dysfunction and apoptosis underlie the pathogenic process in α-β-crystallin desmin-related cardiomyopathy
A Maloyan et al.
CIRCULATION (2005)
Intrasarcoplasmic amyloidosis impairs proteolytic function of proteasomes in cardiomyocytes by compromising substrate uptake
QH Chen et al.
CIRCULATION RESEARCH (2005)
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
S Pattingre et al.
CELL (2005)
Differential activation of stress-response signaling in load-induced cardiac hypertrophy and failure
BA Rothermel et al.
PHYSIOLOGICAL GENOMICS (2005)
Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes
Amal O. Amer et al.
AUTOPHAGY (2005)
Desmin-related cardiomyopathy in transgenic mice: A cardiac amyloidosis
A Sanbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mechanisms of disease: Intermediate filament proteins and their associated diseases
MB Omary et al.
NEW ENGLAND JOURNAL OF MEDICINE (2004)
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar et al.
NATURE GENETICS (2004)
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate et al.
NATURE (2004)
Desmin aggregate formation by R120G αB-crystallin is caused by altered filament interactions and is dependent upon network status in cells
MD Perng et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
α-synuclein is degraded by both autophagy and the proteasome
JL Webb et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Myocytes die by multiple mechanisms in failing human hearts
S Kostin et al.
CIRCULATION RESEARCH (2003)
Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene
XP Qu et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Biomedicine - Toxic proteins in neurodegenerative disease
JP Taylor et al.
SCIENCE (2002)
Expression of R120G-αB-crystallin causes aberrant desmin and αB-crystallin aggregation and cardiomyopathy in mice
XJ Wang et al.
CIRCULATION RESEARCH (2001)
Mouse model of desmin-related cardiomyopathy
XJ Wang et al.
CIRCULATION (2001)
Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
A Kihara et al.
JOURNAL OF CELL BIOLOGY (2001)
Surplus protein myopathies
HH Goebel et al.
NEUROMUSCULAR DISORDERS (2001)
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
Y Kabeya et al.
EMBO JOURNAL (2000)
Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene.
MC Dalakas et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Increased expression of cytoskeletal, linkage, and extracellular proteins in failing human myocardium
A Heling et al.
CIRCULATION RESEARCH (2000)
Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
A Petiot et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)