p-TSA@nano SiO2 as a New and Efficient Nanocatalyst for the One-Pot Multi-component Synthesis of Some Novel 1-Amidoalkyl-2-Naphthols Under Solvent-Free Conditions

Para-toluene sulfonic acid has been embedded on nano SiO2 (p-TSA@nano SiO2) via a simple method and has been characterized by FT-IR, SEM and EDX techniques. The catalytic activity of the newly synthesized nanostructure has been examined in the environmentally friendly synthesis of 1-amidoalkyl-2-naphthols by the one-pot multi-component condensation of 2-naphthol, various aldehydes, and different amides under solvent-free conditions at 90 degrees C. Short reaction times, easy work-up procedure, excellent yields, and preparation of a vast range of the products, in addition with utilizing the p-TSA@nano SiO2, as a new catalytic system that possesses easy handling, and reusability properties, are some highlighted points of the reported procedure. The proposed mechanism of the condensation has also been described.