Journal
PRIMARY CARE
Volume 41, Issue 4, Pages 765-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pop.2014.08.002
Keywords
Renin; Angiotensin; Aldosterone; Review; Combination; Diabetes; Kidney disease; Albuminuria
Categories
Ask authors/readers for more resources
Angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) therapy in hypertensive diabetic patients with macroalbuminuria, microalbuminuria, or normoalbuminuria has been repeatedly shown to improve cardiovascular mortality and reduce the decline in glomerular filtration rate. Renin-angiotensin-aldosterone system (RAAS) blockade in normotensive diabetic patients with normoalbuminuria or microalbuminuria cannot be advocated at present. Dual RAAS inhibition with ACE inhibitors plus ARBs or ACE inhibitors plus direct renin inhibitors has failed to improve cardiovascular or renal outcomes but has predisposed patients to serious adverse events.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available