Journal
PRIMARY CARE
Volume 39, Issue 3, Pages 561-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pop.2012.06.013
Keywords
Pain; Nociception; Neurobiology; Autonomic; Cognitive; Affective
Categories
Funding
- National Institute on Drug Abuse [DA032517]
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This selective review discusses the psychobiological mediation of nociception and pain. Summarizing literature from physiology and neuroscience, first an overview of the neuroanatomic and neurochemical systems underpinning pain perception and modulation is provided. Second, findings from psychological science are used to elucidate cognitive, emotional, and behavioral factors central to the pain experience. This review has implications for clinical practice with patients suffering from chronic pain, and provides strong rationale for assessing and treating pain from a biopsychosocial perspective.
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