Journal
PRENATAL DIAGNOSIS
Volume 32, Issue 4, Pages 336-343Publisher
WILEY
DOI: 10.1002/pd.2933
Keywords
Array CGH; General cytogenetics; DNA; Copy Number Variation; SNP array; Genomic Arrays
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Funding
- European Commission [MEST CT2005 019707]
- IWT [SBO-60848, TBM-090878]
- KUL [PFV/10/016 SymBioSys]
- [FWO-G.A093.11]
- [GOA/12/015]
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Genomic microarrays are now widely used diagnostically for the molecular karyotyping of patients with intellectual disability, congenital anomalies and autistic spectrum disorder and have more recently been applied for the detection of genomic imbalances in prenatal genetic diagnosis. We present an overview of the different arrays, protocols used and discuss methods of genomic array data analysis. (C) 2012 John Wiley & Sons, Ltd.
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