Journal
POULTRY SCIENCE
Volume 92, Issue 9, Pages 2411-2418Publisher
POULTRY SCIENCE ASSOC INC
DOI: 10.3382/ps.2012-02960
Keywords
genistein; hesperidin; summer stress; biomarker; broiler
Categories
Funding
- Special Fund for Agro-Scientific Research in the Public Interest of China [200903003]
- Sindh Agriculture University, Tandojam, Pakistan
- Higher Education Commission of Pakistan
Ask authors/readers for more resources
This study investigated the supplemental effects of the flavonoids genistein and hesperidin for biomarkers of heat stress in broilers reared under persistent summer stress. A total of 360 one-day-old, mixed-sex broiler chickens were divided into 6 treatment groups: control or supplemented with 5 mg of genistein.kg of feed(-1), 20 mg of hesperidin.kg of feed(-1), or a mixture of genistein and hesperidin (1:4) at a dosage of 5 mg.kg(-1), 10 mg.kg(-1), and 20 mg.kg(-1) of feed. Broilers were slaughtered at 42 d and samples were analyzed for hematological profile, creatine kinase, lactate dehydrogenase, and heat shock protein 70 mRNA levels. Results showed that dietary genistein and hesperidin improved (P < 0.05) the weekly performance of broilers particularly during the finisher period. The circulating heterophils and heterophil-to-lymphocyte ratios were found to decrease (P < 0.01) in the treated groups. Moreover, biomarkers of heat stress including the level of creatine kinase, lactate dehydrogenase, and heat shock protein 70 mRNA of breast muscle was also changed (P < 0.01) positively by the dietary compounds with pronounced effects of combined treatments. These findings suggested that genistein and hesperidin could be a prime strategy to ameliorate summer stress effects in broilers; and a combination of both compounds may lead to mutual synergistic effects. It could be suggested that dietary use of both genistein and hesperidin as a feed supplement may offer a potential nutritional strategy in tropical and subtropical regions to overcome the deleterious effects of persistent summer stress in broiler production.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available