Journal
MEDCHEMCOMM
Volume 6, Issue 1, Pages 51-60Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4md00328d
Keywords
-
Ask authors/readers for more resources
Protein-protein interactions are at the heart of most physiopathological processes. As such, they have attracted considerable attention for designing drugs of the future. Although initially considered as high-value but difficult to identify, low molecular weight compounds able to selectively and potently modulate protein-protein interactions have recently reached clinical trials. Along with high-throughput screening of compound libraries, combining structural and computational approaches has boosted this formerly minor area of research into a currently tremendously active field. This review highlights the very recent developments in the rational design of protein-protein interaction inhibitors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available