Spectroscopic and Antibacterial Evaluation of Nano-Hydroxapatite Polyvinyl Alcohol Biocomposite Doped with Microbial-Synthesized Nanogold for Biomedical Applications

Gold nanoparticles were synthesized by locally isolated fungi, Eurotium herbariorum. The biosynthesized nanogold was estimated by color change after the addition of fungal biomass to an aqueous solution of HAuCl4 (1g/L). Transmission electron microscopy (TEM) evaluated that the biosynthesized gold nanoparticles exhibited size range between 15 and 34nm. Hydroxyapatite/polyvinylalcohol biocomposite containing fungal biosynthesized gold nanoparticles at different concentrations were studied for using in biomedical applications. X-ray diffraction (XRD) and Fourier transform infrared (FT-IR) studies test the physical and chemical characteristics of the biocomposite. The biocomposite containing nanogold showed antibacterial activity that increased with nanogold concentration.