Journal
POLYMER INTERNATIONAL
Volume 62, Issue 6, Pages 843-848Publisher
WILEY
DOI: 10.1002/pi.4502
Keywords
oxygen-releasing biomaterials; peroxides; cell survival; tissue engineering
Categories
Funding
- Office of Naval Research Young Investigator Award
- Presidential Early Career Award for Scientists and Engineers (PECASE)
- National Science Foundation CAREER Award [DMR 0847287]
- National Institutes of Health [HL092836, DE019024, EB012597, AR057837, DE021468, HL099073, EB008392]
- Direct For Mathematical & Physical Scien
- Division Of Materials Research [0847287] Funding Source: National Science Foundation
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Due to the increasing demand to generate thick and vascularized tissue-engineered constructs, novel strategies are currently being developed. An emerging example is the generation of oxygen-releasing biomaterials to tackle mass transport and diffusion limitations within engineered tissue constructs. Biomaterials containing oxygen-releasing molecules can be fabricated in various forms, such as hybrid thin films, microparticles or three dimensional scaffolds. In this perspective, we summarize various oxygen-releasing reagents and their potential applications in regenerative engineering. Moreover, we review the main approaches for fabricating oxygen-releasing biomaterials for a range of tissue engineering applications. (c) 2013 Society of Chemical Industry
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