Journal
POLYMER DEGRADATION AND STABILITY
Volume 95, Issue 12, Pages 2233-2240Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.polymdegradstab.2010.09.012
Keywords
Type I collagen; Solution; Thermal denaturation; Kinetics; Model
Categories
Funding
- National Natural Science Foundation of China [20876098/B060805]
- Scientific Research Foundation for the Youth Scholars of Sichuan University [2030804134003]
Ask authors/readers for more resources
To further understand the kinetics of the thermal denaturation of type I collagen, the 16 and 8 mg/mL bovine hide collagen solutions were studied by differential scanning calorimetry at different heating rates. The activation energy of the denaturation process was examined utilizing the differential (Friedman) and the integral (Ozawa-Flynn-Wall) isoconversional methods, and several kinetic models were evaluated using the method of multivariate non-linear regression. Besides, the denaturation behavior was simulated under different temperature conditions. Results showed that the activation energy decreased in a different way at lower and higher degrees of conversion, respectively. A three-state model, in which a reversible step was followed by an irreversible one, was the best of the estimated models to describe the denaturation process, which could be approximated by single-step or two-consecutive-step in terms of temperature conditions. (C) 2010 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available