4.7 Article

Antibacterial activity of cationic polymers: side-chain or main-chain type?

Journal

POLYMER CHEMISTRY
Volume 9, Issue 37, Pages 4611-4616

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8py00665b

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Funding

  1. National Science Foundation for Distinguished Young Scholars [21425417]
  2. Natural Science Foundation of China [21704071]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions

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Imidazolium (Im), quaternary ammonium (Qa), and 1,4-diazabicyclo[2.2.2]octane-1,4-diium (DABCO-diium) cation-based small molecule cationic compounds, and their corresponding side-chain/main-chain cationic polymers were synthesized. The antibacterial activities of the three kinds of synthesized antibacterial agents decreased in the order: main-chain cationic polymers > side-chain cationic polymers > small molecule cationic compounds.

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