4.7 Article

Fabrication of dual-responsive micelles based on the supramolecular interaction of cucurbit[8]uril

Journal

POLYMER CHEMISTRY
Volume 4, Issue 2, Pages 242-245

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2py20549a

Keywords

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Funding

  1. Natural Science Foundation of China [50830106, 21174126]
  2. China National Funds for Distinguished Young Scientists [51025312]
  3. National Basic Research Program of China [2011CB606203]
  4. Open Project of State Key Laboratory of Supramolecular Structure and Materials [SKLSSM201204]

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Biocompatible and dual-responsive micelles were fabricated from a cucurbit[8]uril (CB[8]) connected amphiphilic linear-hyperbranched polymer complex. After addition of adamantaneamine or Na2S2O4, the micelles became larger and exhibited triggered-release of hydrophobic coumarin 102 because of the CB[8]-based host-guest interaction.

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