Journal
JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 3, Pages 148-153Publisher
SAGE PUBLICATIONS LTD
DOI: 10.3184/174751915X14241706062908
Keywords
triazolopyrimidines; pyrimidopyridazines; pyridazinotriazines; triazolopyrimidopyridazinotriazine
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Funding
- Ferdowsi University of Mashhad [3/19530]
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The condensation reaction of 6-acetyl-3-amino-5-aryl-2-phenyl-2,5-dihydropyridazine-4-carbonitrile with triethyl orthoformate and then with hydrazine hydrate to obtain the new fused bicyclic 4-aryl-5-hydrazinyl-3-(1-hydrazonoethyl)-1-phenyl-1,4-dihydropyrimido[4,5-c]pyridazines via the Dimroth rearrangement is reported. Further cyclisation was achieved by the treatment of latter compounds with triethyl orthoformate to afford several derivatives of a novel tetracyclic fused system [1,2,4]triazolo[4 '',3 '':1',6']pyrimido[4',5':3,4]pyridazino[1,6-d][1,2,4]triazine.
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