Related references
Note: Only part of the references are listed.Identification of lysosomal Npc1-binding proteins: Cathepsin D activity is regulated by NPC1
Judit Macias-Vidal et al.
PROTEOMICS (2016)
Cysteine cathepsins are essential in lysosomal degradation of α-synuclein
Ryan P. McGlinchey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Cathepsin Inhibition-Induced Lysosomal Dysfunction Enhances Pancreatic Beta-Cell Apoptosis in High Glucose
Minjeong Jung et al.
PLOS ONE (2015)
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis
Stefan Tholen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease
Martina Malnar et al.
NEUROBIOLOGY OF DISEASE (2014)
The Alzheimer's β-secretase BACE1 localizes to normal presynaptic terminals and to dystrophic presynaptic terminals surrounding amyloid plaques
Patty C. Kandalepas et al.
ACTA NEUROPATHOLOGICA (2013)
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
Carmine Settembre et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Involvement of Cathepsins B and L in Inflammation and Cholesterol Trafficking Protein NPC2 Secretion in Macrophages
Jennifer Hannaford et al.
OBESITY (2013)
Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells
Martina Malnar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Z-Phe-Ala-diazomethylketone (PADK) Disrupts and Remodels Early Oligomer States of the Alzheimer Disease Aβ42 Protein
Xueyun Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Cathepsins S, B and L with aminopeptidases display β-secretase activity associated with the pathogenesis of Alzheimer's disease
Israel Schechter et al.
BIOLOGICAL CHEMISTRY (2011)
Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models
David Butler et al.
PLOS ONE (2011)
Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway
Martina Malnar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2010)
Increased Activity and Altered Subcellular Distribution of Lysosomal Enzymes Determine Neuronal Vulnerability in Niemann-Pick Type C1-Deficient Mice
Asha Amritraj et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Cysteine protease inhibitors reduce brain β-amyloid and β-secretase activity in vivo and are potential Alzheimer's disease therapeutics
Gregory Hook et al.
BIOLOGICAL CHEMISTRY (2007)
Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease
Sarah Mueller-Steiner et al.
NEURON (2006)
The cathepslin D rs17571 polymorphism:: Effects on CSF Tau concentrations in Alzheimer disease
Matthias Riemenschneider et al.
HUMAN MUTATION (2006)
β-secretase activity increases with aging in human, monkey, and mouse brain
H Fukumoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Neuronal and microglial cathepsins in aging and age-related diseases
H Nakanishi
AGEING RESEARCH REVIEWS (2003)
Neuronal loss and brain atrophy in mice lacking cathepsins B and L
U Felbor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Selective neurodegeneration, without neurofibrillary tangles, in a mouse model of Niemann-Pick C disease
DC German et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2001)
Niemann-Pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis
EE Millard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
