4.6 Article

A Liver-Centric Multiscale Modeling Framework for Xenobiotics

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

Multiscale computational model of fluid flow and matrix deformation in decellularized liver

Kenichiro Nishii et al.

JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS (2016)

Article Biochemical Research Methods

libRoadRunner: a high performance SBML simulation and analysis library

Endre T. Somogyi et al.

BIOINFORMATICS (2015)

Article Biotechnology & Applied Microbiology

PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses

Liudmila L. Mazaleuskaya et al.

PHARMACOGENETICS AND GENOMICS (2015)

Article Biochemistry & Molecular Biology

BioModels: ten-year anniversary

Vijayalakshmi Chelliah et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Multidisciplinary Sciences

Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics Simulations

Lars Ole Schwen et al.

PLOS ONE (2015)

Review Gastroenterology & Hepatology

How predictive quantitative modelling of tissue organisation can inform liver disease pathogenesis

Dirk Drasdo et al.

JOURNAL OF HEPATOLOGY (2014)

Article Biochemical Research Methods

Spatio-Temporal Simulation of First Pass Drug Perfusion in the Liver

Lars Ole Schwen et al.

PLOS COMPUTATIONAL BIOLOGY (2014)

Review Medicine, Research & Experimental

Hepatic stellate cells in liver development, regeneration, and cancer

Chunyue Yin et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Mathematical & Computational Biology

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

Rotem Ben-Shachar et al.

THEORETICAL BIOLOGY AND MEDICAL MODELLING (2012)

Article Medicine, Research & Experimental

The virtual liver: a multidisciplinary, multilevel challenge for systems biology

Hermann-Georg Holzhuetter et al.

WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2012)

Article Biochemical Research Methods

Integrating Cellular Metabolism into a Multiscale Whole-Body Model

Markus Krauss et al.

PLOS COMPUTATIONAL BIOLOGY (2012)

Article Biochemical Research Methods

Adhesion Failures Determine the Pattern of Choroidal Neovascularization in the Eye: A Computer Simulation Study

Abbas Shirinifard et al.

PLOS COMPUTATIONAL BIOLOGY (2012)

Article Biochemical Research Methods

Quantification of acetaminophen (paracetamol) in human plasma and urine by stable isotope-dilution GC-MS and GC-MS/MS as pentafluorobenzyl ether derivative

Arne Trettin et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2011)

Article Biochemical Research Methods

A Multi-cell, Multi-scale Model of Vertebrate Segmentation and Somite Formation

Susan D. Hester et al.

PLOS COMPUTATIONAL BIOLOGY (2011)

Article Multidisciplinary Sciences

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration

Stefan Hoehme et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemical Research Methods

Simulating Microdosimetry in a Virtual Hepatic Lobule

John Wambaugh et al.

PLOS COMPUTATIONAL BIOLOGY (2010)

Article Multidisciplinary Sciences

3D Multi-Cell Simulation of Tumor Growth and Angiogenesis

Abbas Shirinifard et al.

PLOS ONE (2009)

Article Biochemical Research Methods

LibSBML: an API library for SBML

Benjamin J. Bornstein et al.

BIOINFORMATICS (2008)

Article Engineering, Electrical & Electronic

CellDesigner 3.5: A versatile modeling tool for biochemical networks

Akira Funahashi et al.

PROCEEDINGS OF THE IEEE (2008)

Article Biochemical Research Methods

Stochastic simulation GUI for biochemical networks

Ravishankar Rao Vallabhajosyula et al.

BIOINFORMATICS (2007)

Article Biochemical Research Methods

SBMLeditor:: effective creation of models in the Systems Biology Markup Language (SBML)

Nicolas Rodriguez et al.

BMC BIOINFORMATICS (2007)

Review Toxicology

Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

Ruth A. Roberts et al.

TOXICOLOGICAL SCIENCES (2007)

Article Biochemical Research Methods

COPASI- A COmplex PAthway SImulator

Stefan Hoops et al.

BIOINFORMATICS (2006)

Review Gastroenterology & Hepatology

Role of Kupffer cells in host defense and liver disease

Manfred Bilzer et al.

LIVER INTERNATIONAL (2006)

Article Pharmacology & Pharmacy

Physiologically based synthetic models of hepatic disposition

C. Anthony Hunt et al.

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS (2006)

Article Biochemical Research Methods

CompuCell, a multi-model framework for simulation of morphogenesis

JA Izaguirre et al.

BIOINFORMATICS (2004)

Article Pharmacology & Pharmacy

Acetaminophen-induced hepatotoxicity

LP James et al.

DRUG METABOLISM AND DISPOSITION (2003)

Review Pathology

In vitro models to study hepatotoxicity

DA Groneberg et al.

TOXICOLOGIC PATHOLOGY (2002)