Journal
CHEMICAL SCIENCE
Volume 6, Issue 7, Pages 4025-4028Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5sc01475a
Keywords
-
Categories
Funding
- EPSRC [EP/H043195/1, EP/L505055/1]
- Engineering and Physical Sciences Research Council [EP/H043195/1] Funding Source: researchfish
- EPSRC [EP/H043195/1] Funding Source: UKRI
Ask authors/readers for more resources
We demonstrate the use of a simple pH swing to control the selection of one of three different guests from aqueous solution by a coordination cage host. Switching between different guests is based on the fact that neutral organic guests bind strongly in the cage due to the hydrophobic effect, but for acidic or basic guests, the charged (protonated or deprotonated) forms are hydrophilic and do not bind. The guests used are adamantane-1,3-dicarboxylic acid (H(2)A) which binds at low pH when it is neutral but not when it is deprotonated; 1-amino-adamantane (B) which binds at high pH when it is neutral but not when it is protonated; and cyclononanone (C) whose binding is not pH dependent and is therefore the default guest at neutral pH. Thus an increase in pH can reversibly switch the host between the three different bound states cage center dot H(2)A (at low pH), cage center dot C (at medium pH), and cage center dot B (at high pH) in succession.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available