Journal
CHEMICAL SCIENCE
Volume 6, Issue 8, Pages 4525-4529Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5sc01772f
Keywords
-
Categories
Funding
- National Basic Research Program of China (973 Program) [2015CB856600]
- National Natural Science Foundation of China [21332009, 21421091]
- Chinese Academy of Sciences
Ask authors/readers for more resources
An Ir-catalyzed asymmetric allylic alkylation of 3-substituted indoles is reported. The reaction provides indoline products containing multiple contiguous stereocenters with high site-, regio-, diastereo- and enantioselectivities in one step from a wide range of readily available starting materials. The key to this method is the high level of diastereocontrol enabled by an iridium catalyst derived from a N-aryl phosphoramidite ligand (Me-THQphos, 1c).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available