Related references
Note: Only part of the references are listed.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story
Feng He et al.
ANNUAL REVIEW OF GENETICS, VOL 49 (2015)
Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor
Xiaojiao Xue et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Therapeutics Based on Stop Codon Readthrough
Kim M. Keeling et al.
ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 15 (2014)
Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3-epi-Deoxynegamycin and Its Leucine Adduct
Akihiro Taguchi et al.
CHEMMEDCHEM (2014)
5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion
Madhuri Bhuvanagiri et al.
EMBO MOLECULAR MEDICINE (2014)
Designer Aminoglycosides That Selectively Inhibit Cytoplasmic Rather than Mitochondrial Ribosomes Show Decreased Ototoxicity A STRATEGY FOR THE TREATMENT OF GENETIC DISEASES
Eli Shulman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Long-term nonsense suppression therapy moderates MPS I-H disease progression
Gwen Gunn et al.
MOLECULAR GENETICS AND METABOLISM (2014)
Toward a Rationale for the PTC124 (Ataluren) Promoted Readthrough of Premature Stop Codons: A Computational Approach and GFP-Reporter Cell-Based Assay
Laura Lentini et al.
MOLECULAR PHARMACEUTICS (2014)
Tobramycin is a suppressor of premature termination codons
Nicola Altamura et al.
JOURNAL OF CYSTIC FIBROSIS (2013)
Intra- and Intermolecular Regulatory Interactions in Upf1, the RNA Helicase Central to Nonsense-Mediated mRNA Decay in Yeast
Feng He et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
A New Series of Small Molecular Weight Compounds Induce Read Through of All Three Types of Nonsense Mutations in the ATM Gene
Liutao Du et al.
MOLECULAR THERAPY (2013)
Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression
Kim M. Keeling et al.
PLOS ONE (2013)
A Lack of Premature Termination Codon Read-Through Efficacy of PTC124 (Ataluren) in a Diverse Array of Reporter Assays
Stuart P. McElroy et al.
PLOS BIOLOGY (2013)
Suppression of premature termination codons as a therapeutic approach
Kim M. Keeling et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2012)
A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation
Tobias Goldmann et al.
EMBO MOLECULAR MEDICINE (2012)
The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse
Dan Wang et al.
MOLECULAR GENETICS AND METABOLISM (2012)
NMD: a multifaceted response to premature translational termination
Stephanie Kervestin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Rescue of nonsense mutations by amlexanox in human cells
Sara Gonzalez-Hilarion et al.
ORPHANET JOURNAL OF RARE DISEASES (2012)
Pharmaceutical therapies to recode nonsense mutations in inherited diseases
Hui-Ling Rose Lee et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Sense from nonsense: therapies for premature stop codon diseases
Laure Bidou et al.
TRENDS IN MOLECULAR MEDICINE (2012)
A reporter system for translational readthrough of stop codons in human cells
Patrick J. Halvey et al.
FEBS OPEN BIO (2012)
Rescue of non-sense mutated p53 tumor suppressor gene by aminoglycosides
Celia Floquet et al.
NUCLEIC ACIDS RESEARCH (2011)
A rapid, inexpensive yeast-based dual-fluorescence assay of programmed-1 ribosomal frameshifting for high-throughput screening
Rasa Rakauskaite et al.
NUCLEIC ACIDS RESEARCH (2011)
Readthrough of Premature Termination Codons in the Adenomatous Polyposis Coli Gene Restores Its Biological Activity in Human Cancer Cells
Celia Floquet et al.
PLOS ONE (2011)
Translational errors: from yeast to new therapeutic targets
Laure Bidou et al.
FEMS YEAST RESEARCH (2010)
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124
Douglas S. Auld et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β039 thalassemia patients
Francesca Salvatori et al.
AMERICAN JOURNAL OF HEMATOLOGY (2009)
Nonaminoglycoside compounds induce readthrough of nonsense mutations
Liutao Du et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations
Igor Nudelman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression
Douglas S. Auld et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A new purple fluorescent color marker for genetic studies in Saccharomyces cerevisiae and Candida albicans
Sabine Keppler-Ross et al.
GENETICS (2008)
PTC124 targets genetic disorders caused by nonsense mutations
Ellen M. Welch et al.
NATURE (2007)
Premature stop codons involved in muscular dystrophies show a broad spectrum of readthrough efficiencies in response to gentamicin treatment
L Bidou et al.
GENE THERAPY (2004)
Leaky termination at premature stop codons antagonizes nonsense-mediated mRNA decay in S-cerevisiae
KM Keeling et al.
RNA (2004)
Nonsense-mediated decay approaches the clinic
JA Holbrook et al.
NATURE GENETICS (2004)
Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough
JW Harger et al.
RNA (2004)
Impact of the six nucleotides downstream of the stop codon on translation termination
O Namy et al.
EMBO REPORTS (2001)
Upf1p, Nmd2p, and Upf3p regulate the decapping and exonucleolytic degradation of both nonsense-containing mRNAs and wild-type mRNAs
F He et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
WR Wang et al.
EMBO JOURNAL (2001)
Nonsense-mediated decay mutants do not affect programmed-1 frameshifting
L Bidou et al.
RNA (2000)
Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
AB Maderazo et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Share Paper
