Related references
Note: Only part of the references are listed.Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
Rafael Rosell et al.
LANCET ONCOLOGY (2012)
Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype
Giulio Metro et al.
LUNG CANCER (2012)
In vitro sequence-dependent synergism between paclitaxel and gefitinib in human lung cancer cell lines
Hua Cheng et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity
Samer Singh et al.
CANCER RESEARCH (2011)
Targeting the Hedgehog Pathway in Cancer: Can the Spines Be Smoothened?
Laurie Ailles et al.
CLINICAL CANCER RESEARCH (2011)
Cancer stem cells: a new framework for the design of tumor therapies
Boyan K. Garvalov et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2011)
Phosphoinositide-3-Kinase Catalytic Alpha and KRAS Mutations are Important Predictors of Resistance to Therapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients with Advanced Non-small Cell Lung Cancer
Vienna Ludovini et al.
JOURNAL OF THORACIC ONCOLOGY (2011)
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study
Caicun Zhou et al.
LANCET ONCOLOGY (2011)
ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
R. R. Singh et al.
ONCOGENE (2011)
Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC
Alexa B. Turke et al.
CANCER CELL (2010)
Hepatocyte Growth Factor Reduces Susceptibility to an Irreversible Epidermal Growth Factor Receptor Inhibitor in EGFR-T790M Mutant Lung Cancer
Tadaaki Yamada et al.
CLINICAL CANCER RESEARCH (2010)
Review: Targeting the Hedgehog pathway in cancer
Sachin Gupta et al.
Therapeutic Advances in Medical Oncology (2010)
Hedgehog Target Genes: Mechanisms of Carcinogenesis Induced by Aberrant Hedgehog Signaling Activation
Y. Katoh et al.
CURRENT MOLECULAR MEDICINE (2009)
Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
Tudor Ciuleanu et al.
LANCET (2009)
Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas
Ioannis P. Gialmanidis et al.
LUNG CANCER (2009)
Hedgehog Pathway Inhibitor HhAntag691 Is a Potent Inhibitor of ABCG2/BCRP and ABCB1/Pgp
Yimao Zhang et al.
NEOPLASIA (2009)
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
Michele Sabbah et al.
DRUG RESISTANCE UPDATES (2008)
Comparative expression of Hedgehog ligands at different stages of prostate carcinoma progression
S. Azoulay et al.
JOURNAL OF PATHOLOGY (2008)
Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
Anne-Pierre Morel et al.
PLOS ONE (2008)
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
James Bean et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers
Daniel B. Costa et al.
LUNG CANCER (2007)
Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells
Murielle Mimeault et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma
Z. Yuan et al.
ONCOGENE (2007)
The role of epithelial-mesenchymal transition in cancer pathology
Marcello Guarino et al.
PATHOLOGY (2007)
Targeting the Hedgehog pathway in cancer
Lee L. Rubin et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Novel D761Y and common secondary T790M mutations in epidermal growth factor receptor - Mutant lung adenocarcinomas with acquired resistance to kinase inhibitors
Marissa N. Balak et al.
CLINICAL CANCER RESEARCH (2006)
Selective modulation of hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes
Maria Kasper et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines
SE Witta et al.
CANCER RESEARCH (2006)
Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
RL Yauch et al.
CLINICAL CANCER RESEARCH (2005)
Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
S Thomson et al.
CANCER RESEARCH (2005)
Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
XL Ma et al.
CARCINOGENESIS (2005)
Communicating with Hedgehogs
JE Hooper et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
W Pao et al.
PLOS MEDICINE (2005)
Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes
RLH Bigelow et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2005)
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
V Palma et al.
DEVELOPMENT (2005)
Hedgehog signaling pathway is a new therapeutic target for patients with breast cancer
M Kubo et al.
CANCER RESEARCH (2004)
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
V Palma et al.
DEVELOPMENT (2004)
The Hedgehog response network: Sensors, switches, and routers
L Lum et al.
SCIENCE (2004)
The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
P Krishnamurthy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
ABCG2 -: a transporter for all seasons
B Sarkadi et al.
FEBS LETTERS (2004)
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
SS Karhadkar et al.
NATURE (2004)
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
SP Thayer et al.
NATURE (2003)
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
DN Watkins et al.
NATURE (2003)
Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro
K Yokoyama et al.
ORAL ONCOLOGY (2001)
Share Paper
