Journal
JACC-CARDIOVASCULAR IMAGING
Volume 8, Issue 6, Pages 710-723Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jcmg.2015.03.005
Keywords
dual-energy CT; molecular CT imaging; spectral CT
Funding
- National Heart, Lung, and Blood Institute [R01 HL111141, R01 HL115150, R01 HL118019]
- GE Healthcare
- Vital Images
- Phillips Healthcare
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Computed tomography (CT) has evolved into a powerful diagnostic tool, and it is impossible to imagine current clinical practice without CT imaging. Because of its widespread availability, ease of clinical application, superb sensitivity for the detection of coronary artery disease, and noninvasive nature, CT has become a valuable tool within the armamentarium of cardiologists. In the past few years, numerous technological advances in CT have occurred, including dual-energy CT, spectral CT, and CT-based molecular imaging. By harnessing the advances in technology, cardiac CT has advanced beyond the mere evaluation of coronary stenosis to an imaging tool that permits accurate plaque characterization, assessment of myocardial perfusion, and even probing of molecular processes that are involved in coronary atherosclerosis. Novel innovations in CT contrast agents and pre-clinical spectral CT devices have paved the way for CT-based molecular imaging. (J Am Coll Cardiol Img 2015;8:710-23) (C) 2015 by the American College of Cardiology Foundation.
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