Related references
Note: Only part of the references are listed.STAT3 induces anoikis resistance, promotes cell invasion and metastatic potential in pancreatic cancer cells
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CARCINOGENESIS (2015)
Inhibition of the JAK2/STAT3 pathway in ovarian cancer results in the loss of cancer stem cell-like characteristics and a reduced tumor burden
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BMC CANCER (2014)
Enriched CD44+/CD24- population drives the aggressive phenotypes presented in triple-negative breast cancer (TNBC)
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ONCOTARGET (2014)
STAT3 Target Genes Relevant to Human Cancers
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Anoikis molecular pathways and its role in cancer progression
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Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells
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NATURE REVIEWS DRUG DISCOVERY (2013)
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PLOS ONE (2013)
STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species
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TOXICOLOGY LETTERS (2013)
Salinomycin induces cell death via inactivation of Stat3 and downregulation of Skp2
K. H. Koo et al.
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Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress
K. Ketola et al.
BRITISH JOURNAL OF CANCER (2012)
CD44+/CD24-/low cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome
Michael O. Idowu et al.
HUMAN PATHOLOGY (2012)
The evolving concept of cancer and metastasis stem cells
Irene Baccelli et al.
JOURNAL OF CELL BIOLOGY (2012)
Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies
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JOURNAL OF CLINICAL ONCOLOGY (2012)
Cancer stem cells and their potential implications for the treatment of solid tumors
B. A. Grotenhuis et al.
JOURNAL OF SURGICAL ONCOLOGY (2012)
Epigenetic alterations involved in cancer stem cell reprogramming
Purificacion Munoz et al.
MOLECULAR ONCOLOGY (2012)
Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species
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PLOS ONE (2012)
Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo
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JOURNAL OF CELL SCIENCE (2011)
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
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JOURNAL OF CLINICAL INVESTIGATION (2011)
The JAK2/STAT3 signaling pathway is required for growth of CD44+CD24- stem cell-like breast cancer cells in human tumors
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JOURNAL OF CLINICAL INVESTIGATION (2011)
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype
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JOURNAL OF CLINICAL PATHOLOGY (2011)
Cyclin D as a therapeutic target in cancer
Elizabeth A. Musgrove et al.
NATURE REVIEWS CANCER (2011)
Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Apoptosis and cancer stem cells: Implications for apoptosis targeted therapy
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BIOCHEMICAL PHARMACOLOGY (2010)
Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation
Hsiao-Ling Cheng et al.
MOLECULAR CANCER (2010)
A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells
Li Lin et al.
NEOPLASIA (2010)
Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
Piyush B. Gupta et al.
CELL (2009)
STAT3 as a Central Regulator of Tumor Metastases
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CURRENT MOLECULAR MEDICINE (2009)
Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs
Vasundhra Kashyap et al.
STEM CELLS AND DEVELOPMENT (2009)
Cross talk Initiated by Endothelial Cells Enhances Migration and Inhibits Anoikis of Squamous Cell Carcinoma Cells through STAT3/Akt/ERK Signaling
Kathleen G. Neiva et al.
NEOPLASIA (2009)
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
Christophe Ginestier et al.
CELL STEM CELL (2007)
Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance
Jiangbing Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer
Marjan Berishaj et al.
BREAST CANCER RESEARCH (2007)
Cyclin D1 is transcriptionally regulated by and required for transformation by activated signal transducer and activator of transcription 3
K Leslie et al.
CANCER RESEARCH (2006)
Activation of Stat3 in primary tumors from high-risk breast cancer patients is associated with elevated levels of activated Src and survivin expression
N Diaz et al.
CLINICAL CANCER RESEARCH (2006)
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
D Ponti et al.
CANCER RESEARCH (2005)
Cyclin D1 in breast cancer pathogenesis
A Arnold et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
G Dontu et al.
GENES & DEVELOPMENT (2003)
Prospective identification of tumorigenic breast cancer cells
M Al-Hajj et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
New functions for the matrix metalloproteinases in cancer progression
M Egeblad et al.
NATURE REVIEWS CANCER (2002)
Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
WM Burke et al.
ONCOGENE (2001)