Journal
HEALTH & PLACE
Volume 34, Issue -, Pages 287-295Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.healthplace.2015.06.001
Keywords
Asthma; Traffic; Air pollution; Spatial epidemiology; Atopy
Categories
Funding
- Health Canada [4500204321]
- Natural Resources Canada
- Canadian Institutes for Health Research [MOP-64463]
Ask authors/readers for more resources
Findings from the Toronto Child Health Evaluation Questionnaire (TCHEQ) study indicate that early childhood exposure to traffic related air pollution (TRAP) is related to the onset of atopic childhood asthma. To test this hypothesis further, we investigated whether spatial patterns in the birth neighbourhood of TCHEQ subjects with atopic asthma (136 of 909 schoolchildren in grades 1-2) could be explained by TRAP and other risk factors. If a causal relationship exists between early childhood residential exposure to TRAP and the development of atopic asthma, we hypothesise that (1) clusters of current asthma should exist around the place of residence at birth, and (2) accounting for residential concentrations of TRAP at birth should explain some of the autocorrelation. Several high asthma clusters were observed. Adjusting for TRAP completely explained one cluster; elsewhere, clusters were only partially explained by TRAP. Findings suggest that exposure during early childhood to TRAP in Toronto is an important contributor to the development of the atopic asthma phenotype and reveal the likely importance of other risk factors not measured in the fixed effects of the model. (C) 2015 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available