4.6 Article

Directed Evolution of a Yeast-Displayed HIV-1 SOSIP gp140 Spike Protein toward Improved Expression and Affinity for Conformational Antibodies

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Nicole A. Doria-Rose et al.

NATURE (2014)

Review Biochemical Research Methods

Vaccine design: emerging concepts and renewed optimism

Sebastian K. Grimm et al.

CURRENT OPINION IN BIOTECHNOLOGY (2013)

Article Biochemistry & Molecular Biology

Rapid Conformational Epitope Mapping of Anti-gp120 Antibodies with a Designed Mutant Panel Displayed on Yeast

Jordi Mata-Fink et al.

JOURNAL OF MOLECULAR BIOLOGY (2013)

Article Multidisciplinary Sciences

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

Hua-Xin Liao et al.

NATURE (2013)

Editorial Material Medicine, General & Internal

Mapping the Journey to an HIV Vaccine

Margaret Ackerman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Multidisciplinary Sciences

Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

Rajesh P. Ringe et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

Jean-Philippe Julien et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

Dmitry Lyumkis et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

Joseph Jardine et al.

SCIENCE (2013)

Review Medicine, Research & Experimental

Emerging Concepts on the Role of Innate Immunity in the Prevention and Control of HIV Infection

Margaret E. Ackerman et al.

ANNUAL REVIEW OF MEDICINE, VOL 63 (2012)

Article Biotechnology & Applied Microbiology

B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

Barton F. Haynes et al.

NATURE BIOTECHNOLOGY (2012)

Article Biochemistry & Molecular Biology

Evolution of an HIV glycan-dependent broadly neutralizing antibody epitope through immune escape

Penny L. Moore et al.

NATURE MEDICINE (2012)

Article Multidisciplinary Sciences

HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120

James M. Kovacs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biochemistry & Molecular Biology

Fine epitope mapping of monoclonal antibodies against hemagglutinin of a highly pathogenic H5N1 influenza virus using yeast surface display

Thomas Han et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Review Biochemistry & Molecular Biology

Limitations to the structure-based design of HIV-1 vaccine immunogens

Marc H. V. Van Regenmortel

JOURNAL OF MOLECULAR RECOGNITION (2011)

Article Multidisciplinary Sciences

Broad neutralization coverage of HIV by multiple highly potent antibodies

Laura M. Walker et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

Secretion-and-capture cell-surface display for selection of target-binding proteins

J. A. Rakestraw et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2011)

Article Multidisciplinary Sciences

Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold

Mihai L. Azoitei et al.

SCIENCE (2011)

Article Multidisciplinary Sciences

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Johannes F. Scheid et al.

SCIENCE (2011)

Article Microbiology

Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

Iliyana Mikell et al.

PLOS PATHOGENS (2011)

Review Medicine, Research & Experimental

Toward an Antibody-Based HIV-1 Vaccine

James A. Hoxie

ANNUAL REVIEW OF MEDICINE (2010)

Review Biotechnology & Applied Microbiology

Engineering of glycosylation in yeast and other fungi: current state and perspectives

Karen De Pourcq et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Review Immunology

Correlates of Protection Induced by Vaccination

Stanley A. Plotkin

CLINICAL AND VACCINE IMMUNOLOGY (2010)

Review Immunology

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

Laura M. Walker et al.

CURRENT OPINION IN IMMUNOLOGY (2010)

Article Multidisciplinary Sciences

Elicitation of structure-specific antibodies by epitope scaffolds

Gilad Ofek et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Editorial Material Microbiology

Few and Far Between: How HIV May Be Evading Antibody Avidity

Joshua S. Klein et al.

PLOS PATHOGENS (2010)

Article Biochemical Research Methods

Engineering complex-type N-glycosylation in Pichia pastoris using GlycoSwitch technology

Pieter P. Jacobs et al.

NATURE PROTOCOLS (2009)

Article Multidisciplinary Sciences

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Lei Chen et al.

SCIENCE (2009)

Article Immunology

Challenges for structure-based HIV vaccine design

William R. Schief et al.

CURRENT OPINION IN HIV AND AIDS (2009)

Article Biochemistry & Molecular Biology

Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling

Benjamin J. Hackel et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Multidisciplinary Sciences

Highly L and D enantioselective variants of horseradish peroxidase discovered by an ultrahigh-throughput selection method

Eugene Antipov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies

Gary Frey et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Humanization of yeast to produce complex terminally sialylated glycoproteins

Stephen R. Hamilton et al.

SCIENCE (2006)

Article Biotechnology & Applied Microbiology

A flow cytometric assay for screening improved heterologous protein secretion in yeast

J. Andy Rakestraw et al.

BIOTECHNOLOGY PROGRESS (2006)

Article Biochemical Research Methods

Gene Designer: a synthetic biology tool for constructing artificial DNA segments

Alan Villalobos et al.

BMC BIOINFORMATICS (2006)

Article Biochemistry & Molecular Biology

Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast

YS Kim et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)

Article Biochemical Research Methods

Isolating and engineering human antibodies using yeast surface display

Ginger Chao et al.

NATURE PROTOCOLS (2006)

Article Biotechnology & Applied Microbiology

Yeast surface display of a noncovalent MHC class II heterodimer complexed with antigenic peptide

ET Boder et al.

BIOTECHNOLOGY AND BIOENGINEERING (2005)

Article Biochemistry & Molecular Biology

Improved design of an antigen with enhanced specificity for the broadly HIV-neutralizing antibody b12

R Pantophlet et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2004)

Article Multidisciplinary Sciences

Production of complex human glycoproteins in yeast

SR Hamilton et al.

SCIENCE (2003)

Article Multidisciplinary Sciences

Rapid evolution of the neutralizing antibody response to HIV type 1 infection

DD Richman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Antibody neutralization and escape by HIV-1

XP Wei et al.

NATURE (2003)

Article Multidisciplinary Sciences

Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity

ET Boder et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)