Related references
Note: Only part of the references are listed.A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition
B. Bedessem et al.
MATHEMATICAL BIOSCIENCES (2014)
Hypoxia-inducible factor (HIF) network: insights from mathematical models
Miguel A. S. Cavadas et al.
CELL COMMUNICATION AND SIGNALING (2013)
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network
Lan K. Nguyen et al.
JOURNAL OF CELL SCIENCE (2013)
Proteostasis Modulators Prolong Missense VHL Protein Activity and Halt Tumor Progression
Chunzhang Yang et al.
CELL REPORTS (2013)
Effect of hypoxia-inducible factor 1-alpha on hypoxia/reoxygenation-induced apoptosis in primary neonatal rat cardiomyocytes
Xiaoou Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)
Up-regulation of hypoxia inducible factor-1α by cobalt chloride correlates with proliferation and apoptosis in PC-2 cells
Zhi-Jun Dai et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2012)
On the importance of the submicrovascular network in a computational model of tumour growth
Anne-Cecile Lesart et al.
MICROVASCULAR RESEARCH (2012)
Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival
Elisa Conde et al.
PLOS ONE (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
VHL Gene Mutations and Their Effects on Hypoxia Inducible Factor HIFα: Identification of Potential Driver and Passenger Mutations
Markus P. Rechsteiner et al.
CANCER RESEARCH (2011)
Reciprocal influence of the p53 and the hypoxic pathways
A. Sermeus et al.
CELL DEATH & DISEASE (2011)
Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
Agon Hyseni et al.
CELLULAR ONCOLOGY (2011)
Chemical Basis for the Selectivity of the von Hippel Lindau Tumor Suppressor pVHL for Prolyl-Hydroxylated HIF-1α
Christopher J. R. Illingworth et al.
BIOCHEMISTRY (2010)
The role of HIF-1 in up-regulating MICA expression on human renal proximal tubular epithelial cells during hypoxia/reoxygenation
Lei Luo et al.
BMC CELL BIOLOGY (2010)
Stress-specific response of the p53-Mdm2 feedback loop
Alexander Hunziker et al.
BMC SYSTEMS BIOLOGY (2010)
Structural Analysis to Determine the Core of Hypoxia Response Network
Monika Heiner et al.
PLOS ONE (2010)
Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications
Dan Cao et al.
BMC CANCER (2009)
Impact of cyclic hypoxia on HIF-1 alpha regulation in endothelial cells - new insights for anti-tumor treatments
Philippe Martinive et al.
FEBS JOURNAL (2009)
Construction of Mutant TKGFP for Real-Time Imaging of Temporal Dynamics of HIF-1 Signal Transduction Activity Mediated by Hypoxia and Reoxygenation in Tumors in Living Mice
Chia-Hung Hsieh et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Real-Time Imaging of HIF-1α Stabilization and Degradation
Ekaterina Moroz et al.
PLOS ONE (2009)
CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response
Silvia Filippi et al.
EMBO JOURNAL (2008)
Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing
U. Berchner-Pfannschmidt et al.
EUROPEAN RESPIRATORY JOURNAL (2008)
Induction of HIF-1 alpha Expression by Intermittent Hypoxia: Involvement of NADPH Oxidase, Ca2+ Signaling, Prolyl Hydroxylases, and mTOR
Guoxiang Yuan et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Three autocrine feedback loops determine HIF1α expression in chronic hypoxia
Amina A. Qutub et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
Identification of a common subnuclear localization signal
Karim Mekhail et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
HIF-dependent antitumorigenic effect of antioxidants in vivo
Ping Gao et al.
CANCER CELL (2007)
Pathway switching explains the sharp response characteristic of hypoxia response network
Yihai Yu et al.
PLOS COMPUTATIONAL BIOLOGY (2007)
Mutant p53 facilitates pro-angiogenic, hyperproliferative phenotype in response to chronic relative hypoxia
Chandrashekhar D. Kamat et al.
CANCER LETTERS (2007)
Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting
Mark W. Dewhirst
CANCER RESEARCH (2007)
Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer
Ern Yu Tan et al.
BREAST CANCER RESEARCH (2007)
Preconditioning of the tumor vasculature and tumor cells by intermittent hypoxia:: Implications for anticancer therapies
Philippe Martinive et al.
CANCER RESEARCH (2006)
Cell-type-specific regulation of degradation of hypoxia-inducible factor 1α:: Role of subcellular compartmentalization
Xiaowei Zheng et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness
T Jokilehto et al.
CLINICAL CANCER RESEARCH (2006)
Accumulation and nuclear import of HIF1 alpha during high and low oxygen concentration in skeletal muscle cells in primary culture
HP Kubis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2005)
Induction of the von Hippel-Lindau tumor suppressor gene by late hypoxia limits HIF-1 expression
J Karhausen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2005)
Expression of hypoxia-inducible factor-1α in esophageal squamous cell carcinoma
T Matsuyama et al.
CANCER SCIENCE (2005)
Hypoxia stimulates proliferation of human hepatoma cells through the induction of hexokinase II expression
GY Gwak et al.
JOURNAL OF HEPATOLOGY (2005)
Properties of switch-like bioregulatory networks studied by simulation of the hypoxia response control system
KW Kohn et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein
I Groulx et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Structural basis for the recognition of hydroxyproline in αIF-1α by pVHL
WC Hon et al.
NATURE (2002)
Hypoxia - A key regulatory factor in tumour growth
AL Harris
NATURE REVIEWS CANCER (2002)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Targeting of HIF-α to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
P Jaakkola et al.
SCIENCE (2001)
Hypoxia inhibits G1/S transition through regulation of p27 expression
LB Gardner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors
MV Blagosklonny
ONCOGENE (2001)
Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function
M Krieg et al.
ONCOGENE (2000)
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
KL Talks et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation
PM Kang et al.
CIRCULATION RESEARCH (2000)