4.6 Article

Celastrol Stimulates Hypoxia-Inducible Factor-1 Activity in Tumor Cells by Initiating the ROS/Akt/p70S6K Signaling Pathway and Enhancing Hypoxia-Inducible Factor-1α Protein Synthesis

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Celastrol inhibits gastric cancer growth by induction of apoptosis and autophagy

Hyun-Woo Lee et al.

BMB REPORTS (2014)

Review Biochemistry & Molecular Biology

Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses

Joanna Obacz et al.

MOLECULAR CANCER (2013)

Article Biochemistry & Molecular Biology

Celastrol protects human neuroblastoma SH-SY5Y cells from rotenone-induced injury through induction of autophagy

Yong-Ning Deng et al.

NEUROCHEMISTRY INTERNATIONAL (2013)

Article Biochemistry & Molecular Biology

Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cells

Lili Guo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)

Review Toxicology

HIF-prolyl hydroxylases and cardiovascular diseases

Sucharita Sen Banerjee et al.

TOXICOLOGY MECHANISMS AND METHODS (2012)

Article Biochemistry & Molecular Biology

Celastrus-derived Celastrol Suppresses Autoimmune Arthritis by Modulating Antigen-induced Cellular and Humoral Effector Responses

Shivaprasad H. Venkatesha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells

Shantel E. Walcott et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2010)

Article Biochemistry & Molecular Biology

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

Ahmed Chadli et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Clinical Neurology

Celastrol causes apoptosis and cell cycle arrest in rat glioma cells

Pengfei Ge et al.

NEUROLOGICAL RESEARCH (2010)

Editorial Material Cell Biology

Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia

Nathalie M. Mazure et al.

AUTOPHAGY (2009)

Article Oncology

CELASTROL POTENTIATES RADIOTHERAPY BY IMPAIRMENT OF DNA DAMAGE PROCESSING IN HUMAN PROSTATE CANCER

Yao Dai et al.

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)

Article Biochemistry & Molecular Biology

The Akt/mTOR Pathway Assures the Synthesis of HIF-1α Protein in a Glucose- and Reoxygenation-dependent Manner in Irradiated Tumors

Hiroshi Harada et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Characterization of Celastrol to Inhibit Hsp90 and Cdc37 Interaction

Tao Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains

Gregory Bellot et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

Huafeng Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

Significance of HIF-1-active cells in angiogenesis and radioresistance

H. Harada et al.

ONCOGENE (2007)

Article Biochemistry & Molecular Biology

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

A. Hamacher-Brady et al.

CELL DEATH AND DIFFERENTIATION (2007)

Article Urology & Nephrology

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure

Wanja M. Bernhardt et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2006)

Article Biochemistry & Molecular Biology

Hypoxia up-regulates prolyl hydroxylase activity - A feedback mechansim that limits HIF-1 responses during reoxygenation

G D'Angelo et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

A new mathematical model for relative quantification in real-time RT-PCR

MW Pfaffl

NUCLEIC ACIDS RESEARCH (2001)