Related references
Note: Only part of the references are listed.Polarity gene discs large homolog 1 regulates the generation of memory T cells
Grzegorz B. Gmyrek et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Incidence and Phenotype of Inflammatory Bowel Disease Based on Results From the Asia-Pacific Crohn's and Colitis Epidemiology Study
Siew C. Ng et al.
GASTROENTEROLOGY (2013)
Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
Katja Christodoulou et al.
GUT (2013)
Hunting human disease genes: lessons from the past, challenges for the future
Liam R. Brunham et al.
HUMAN GENETICS (2013)
The trend in newly diagnosed Crohn's disease and extraintestinal manifestations of Crohn's disease in central China: a retrospective study of a single center
Fengming Yi et al.
EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2012)
Disease gene identification strategies for exome sequencing
Christian Gilissen et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2012)
Exome sequencing identifies novel compound heterozygous mutations of IL-10 receptor 1 in neonatal-onset Crohn's disease
H. Mao et al.
GENES AND IMMUNITY (2012)
New therapies for inflammatory bowel disease: from the bench to the bedside
Silvio Danese
GUT (2012)
Rare and common variants: twenty arguments
Greg Gibson
NATURE REVIEWS GENETICS (2012)
Dysregulation of Cell Polarity Proteins Synergize with Oncogenes or the Microenvironment to Induce Invasive Behavior in Epithelial Cells
Samit Chatterjee et al.
PLOS ONE (2012)
A Knowledge-Based Method for Association Studies on Complex Diseases
Alireza Nazarian et al.
PLOS ONE (2012)
Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function
Lisa A. Humphries et al.
PLOS ONE (2012)
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
Jacob A. Tennessen et al.
SCIENCE (2012)
What is complex about complex disorders?
Kevin J. Mitchell
GENOME BIOLOGY (2012)
Future Therapeutic Approaches for Inflammatory Bowel Diseases
Scott E. Plevy et al.
GASTROENTEROLOGY (2011)
Regulation of Homeostasis and Inflammation in the Intestine
Thomas T. MacDonald et al.
GASTROENTEROLOGY (2011)
Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
Warren Strober et al.
GASTROENTEROLOGY (2011)
Recent Insights Into the Genetics of Inflammatory Bowel Disease
Judy H. Cho et al.
GASTROENTEROLOGY (2011)
Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease
Elizabeth A. Worthey et al.
GENETICS IN MEDICINE (2011)
Guidelines for the management of inflammatory bowel disease in adults
Craig Mowat et al.
GUT (2011)
dbNSFP: A Lightweight Database of Human Nonsynonymous SNPs and Their Functional Predictions
Xiaoming Liu et al.
HUMAN MUTATION (2011)
Update on the Heritability of Inflammatory Bowel Disease: The Importance of Twin Studies
Steven R. Brant
INFLAMMATORY BOWEL DISEASES (2011)
Protein Kinase Cα Promotes Cell Migration through a PDZ-Dependent Interaction with its Novel Substrate Discs Large Homolog 1 (DLG1)
Audrey K. O'Neill et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
What can exome sequencing do for you?
Jacek Majewski et al.
JOURNAL OF MEDICAL GENETICS (2011)
Fast and accurate long-read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2010)
Genetic Heterogeneity in Human Disease
Jon McClellan et al.
CELL (2010)
GWAS: heritability missing in action?
Angus J. Clarke et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2010)
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna et al.
GENOME RESEARCH (2010)
Exome sequencing: the sweet spot before whole genomes
Jamie K. Teer et al.
HUMAN MOLECULAR GENETICS (2010)
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
Gert Van Assche et al.
JOURNAL OF CROHNS & COLITIS (2010)
Infant colitis-it's in the genes
Erik-Oliver Glocker et al.
LANCET (2010)
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Andre Franke et al.
NATURE GENETICS (2010)
MutationTaster evaluates disease-causing potential of sequence alterations
Jana Marie Schwarz et al.
NATURE METHODS (2010)
DLG1/SAP97 modulates transforming growth factor α bioavailability
Anne-Laure Surena et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
SOAP2: an improved ultrafast tool for short read alignment
Ruiqiang Li et al.
BIOINFORMATICS (2009)
Finding the missing heritability of complex diseases
Teri A. Manolio et al.
NATURE (2009)
Decanalization and the origin of complex disease
Greg Gibson
NATURE REVIEWS GENETICS (2009)
Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor
Erik-Oliver Glocker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The diploid genome sequence of an Asian individual
Jun Wang et al.
NATURE (2008)
Genetic Mapping in Human Disease
David Altshuler et al.
SCIENCE (2008)
Discs large (DIg1) complexes in lymphocyte activation
R Xavier et al.
JOURNAL OF CELL BIOLOGY (2004)
SIFT: predicting amino acid changes that affect protein function
PC Ng et al.
NUCLEIC ACIDS RESEARCH (2003)
Familial Crohn's disease in single or multiple first-degree relatives
HJ Freeman
JOURNAL OF CLINICAL GASTROENTEROLOGY (2002)