4.6 Article

Ubiquilin-1 Overexpression Increases the Lifespan and Delays Accumulation of Huntingtin Aggregates in the R6/2 Mouse Model of Huntington's Disease

Related references

Note: Only part of the references are listed.
Article Neurosciences

Unbiased screen reveals ubiquilin-1 and-2 highly associated with huntingtin inclusions

Nicola J. Rutherford et al.

BRAIN RESEARCH (2013)

Article Clinical Neurology

Ubiquilin-1 immunoreactivity is concentrated on Hirano bodies and dystrophic neurites in Alzheimer's disease brains

J. Satoh et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2013)

Article Clinical Neurology

Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion

Johannes Brettschneider et al.

ACTA NEUROPATHOLOGICA (2012)

Article Biochemistry & Molecular Biology

IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux

Huikyong Lee et al.

HUMAN MOLECULAR GENETICS (2012)

Article Cell Biology

Indirect inhibition of 26S proteasome activity in a cellular model of Huntington's disease

Mark S. Hipp et al.

JOURNAL OF CELL BIOLOGY (2012)

Article Neurosciences

Association of UBQLN1 mutation with Brown-Vialetto-Van Laere syndrome but not typical ALS

Paloma Gonzalez-Perez et al.

NEUROBIOLOGY OF DISEASE (2012)

Article Endocrinology & Metabolism

Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease

Pengxiang She et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)

Article Multidisciplinary Sciences

Mutations in UBQLN2 cause dominant X-linked juvenile and adult-onset ALS and ALS/dementia

Han-Xiang Deng et al.

NATURE (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy

Cara Rothenberg et al.

HUMAN MOLECULAR GENETICS (2010)

Article Neurosciences

Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease

Marta Martinez-Vicente et al.

NATURE NEUROSCIENCE (2010)

Article Biochemistry & Molecular Biology

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

Elsa-Noah N'Diaye et al.

EMBO REPORTS (2009)

Article Cell Biology

Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD

Precious J. Lim et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Neurosciences

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

Liliana Menalled et al.

NEUROBIOLOGY OF DISEASE (2009)

Article Biochemistry & Molecular Biology

Herp enhances ER-associated protein degradation by recruiting ubiquilins

Tae-Yeon Kim et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)

Review Biochemistry & Molecular Biology

Huntington's disease: degradation of mutant huntingtin by autophagy

Sovan Sarkar et al.

FEBS JOURNAL (2008)

Article Cell Biology

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

Martin L. Duennwald et al.

GENES & DEVELOPMENT (2008)

Article Biochemistry & Molecular Biology

ubiquilin antagonizes presenilin and promotes neurodegeneration in Drosophila

Atish Ganguly et al.

HUMAN MOLECULAR GENETICS (2008)

Review Cell Biology

The endoplasmic reticulum and the unfolded protein response

Jyoti D. Malhotra et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2007)

Article Multidisciplinary Sciences

IRE1 signaling affects cell fate during the unfolded protein response

Jonathan H. Lin et al.

SCIENCE (2007)

Article Biochemistry & Molecular Biology

Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins

Hongmin Wang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Multidisciplinary Sciences

Global changes to the ubiquitin system in Huntington's disease

Eric J. Bennett et al.

NATURE (2007)

Review Cell Biology

Signal integration in the endoplasmic reticulum unfolded protein response

David Ron et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Review Medicine, General & Internal

Huntington's disease

Francis O. Walker

LANCET (2007)

Article Biochemistry & Molecular Biology

Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin

H Wang et al.

HUMAN MOLECULAR GENETICS (2006)

Article Biochemistry & Molecular Biology

Identification of ubiquitin-interacting proteins in purified polyglutamine aggregates

H Doi et al.

FEBS LETTERS (2004)

Article Neurosciences

Standardization and statistical approaches to therapeutic trials in the R6/2 mouse

E Hockly et al.

BRAIN RESEARCH BULLETIN (2003)

Article Biochemistry & Molecular Biology

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

EJ Slow et al.

HUMAN MOLECULAR GENETICS (2003)

Article Biochemistry & Molecular Biology

Polyglutamine aggregates stimulate ER stress signals and caspase-12 activation

Y Kouroku et al.

HUMAN MOLECULAR GENETICS (2002)

Review Biochemistry & Molecular Biology

The glucose-regulated proteins: stress induction and clinical applications

AS Lee

TRENDS IN BIOCHEMICAL SCIENCES (2001)

Article Biochemistry & Molecular Biology

Neurological abnormalities in a knock-in mouse model of Huntington's disease

CH Lin et al.

HUMAN MOLECULAR GENETICS (2001)