Related references
Note: Only part of the references are listed.The importance of interactions with helix 5 in determining the efficacy of β-adrenoceptor ligands
Tony Warne et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
Optimising the combination of thermostabilising mutations in the neurotensin receptor for structure determination
Yoko Shibata et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
Molecular signatures of G-protein-coupled receptors
A. J. Venkatakrishnan et al.
NATURE (2013)
Membrane Protein Structure Determination Using Crystallography and Lipidic Mesophases: Recent Advances and Successes
Martin Caffrey et al.
BIOCHEMISTRY (2012)
Lifting the lid on GPCRs: the role of extracellular loops
M. Wheatley et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Agonist-bound structures of G protein-coupled receptors
Guillaume Lebon et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2012)
Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design
Miles Congreve et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Structure of the agonist-bound neurotensin receptor
Jim F. White et al.
NATURE (2012)
High-resolution crystal structure of human protease-activated receptor 1
Cheng Zhang et al.
NATURE (2012)
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
Wei Liu et al.
SCIENCE (2012)
Crystal Structures of a Stabilized β1-Adrenoceptor Bound to the Biased Agonists Bucindolol and Carvedilol
Tony Warne et al.
STRUCTURE (2012)
New insights from structural biology into the druggability of G protein-coupled receptors
Jonathan S. Mason et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
Engineering an Ultra-Thermostable β1-Adrenoceptor
Jennifer L. Miller et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A2A Receptor
Guillaume Lebon et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation
Guillaume Lebon et al.
NATURE (2011)
The structural basis for agonist and partial agonist action on a β1-adrenergic receptor
Tony Warne et al.
NATURE (2011)
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
Soren G. F. Rasmussen et al.
NATURE (2011)
Structure and function of an irreversible agonist-β2 adrenoceptor complex
Daniel M. Rosenbaum et al.
NATURE (2011)
Crystal structure of the β2 adrenergic receptor-Gs protein complex
Soren G. F. Rasmussen et al.
NATURE (2011)
Two distinct conformations of helix 6 observed in antagonist-bound structures of a β1-adrenergic receptor
Rouslan Moukhametzianov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Structure of an Agonist-Bound Human A2A Adenosine Receptor
Fei Xu et al.
SCIENCE (2011)
Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine
Andrew S. Dore et al.
STRUCTURE (2011)
HYPONATREMIA: MECHANISMS AND NEWER TREATMENTS
Mark L. Zeidel
ENDOCRINE PRACTICE (2010)
Conserved Binding Mode of Human β2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography
Daniel Wacker et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Crystallizing Membrane Proteins for Structure Determination: Use of Lipidic Mesophases
Martin Caffrey
ANNUAL REVIEW OF BIOPHYSICS (2009)
Engineering G protein-coupled receptors to facilitate their structure determination
Christopher G. Tate et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)
Thermostabilization of the Neurotensin Receptor NTS1
Yoko Shibata et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
The structure and function of G-protein-coupled receptors
Daniel M. Rosenbaum et al.
NATURE (2009)
Crystallizing membrane proteins using lipidic mesophases
Martin Caffrey et al.
NATURE PROTOCOLS (2009)
Development and crystallization of a minimal thermostabilised G protein-coupled receptor
Tony Warne et al.
PROTEIN EXPRESSION AND PURIFICATION (2009)
Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor
Christophe D. Proulx et al.
MOLECULAR PHARMACOLOGY (2008)
Structure of a β1-adrenergic G-protein-coupled receptor
Tony Warne et al.
NATURE (2008)
Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor
Francesca Magnani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Conformational thermostabilization of the β1-adrenergic receptor in a detergent-resistant form
Maria J. Serrano-Vega et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
Veli-Pekka Jaakola et al.
SCIENCE (2008)
A specific cholesterol binding site is established by the 2.8 Å structure of the human β2-adrenergic receptor
Michael A. Hanson et al.
STRUCTURE (2008)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
Daniel M. Rosenbaum et al.
SCIENCE (2007)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
Ian W. Davis et al.
NUCLEIC ACIDS RESEARCH (2007)
Beta-blockers show inverse agonism to a novel constitutively active mutant of β1-adrenoceptor
Maruf Ahmed et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2006)
The integration of macromolecular diffraction data
AGW Leslie
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Scaling and assessment of data quality
P Evans
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Expression and purification of truncated, non-glycosylated turkey beta-adrenergic receptors for crystallization
T Warne et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2003)
Metal-ligand geometry relevant to proteins and in proteins: sodium and potassium
MM Harding
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2002)
Allosteric modulation of A2A adenosine receptors by amiloride analogues and sodium ions
ZG Gao et al.
BIOCHEMICAL PHARMACOLOGY (2000)