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JOURNAL OF VIROLOGY (2009)
Apolipoprotein E but Not B Is Required for the Formation of Infectious Hepatitis C Virus Particles
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JOURNAL OF VIROLOGY (2009)
Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity
Zhen-yong Keck et al.
JOURNAL OF VIROLOGY (2009)
Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
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JOURNAL OF VIROLOGY (2009)
Safety, immunogenicity, and efficacy of quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine in women aged 24-45 years: a randomised, double-blind trial
Nubia Munoz et al.
LANCET (2009)
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
Alexander Ploss et al.
NATURE (2009)
Depletion of interfering antibodies in chronic hepatitis C patients and vaccinated chimpanzees reveals broad cross-genotype neutralizing activity
Pei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor
David M. Owen et al.
VIROLOGY (2009)
A single point mutation in E2 enhances hepatitis C virus infectivity and alters lipoprotein association of viral particles
Wanyin Tao et al.
VIROLOGY (2009)
What Are the Prospects for Controlling Hepatitis C?
Paul Klenerman et al.
PLOS MEDICINE (2009)
The Global Spread of Hepatitis C Virus 1a and 1b: A Phylodynamic and Phylogeographic Analysis
Gkikas Magiorkinis et al.
PLOS MEDICINE (2009)
Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry
Hsiao-Fen Li et al.
JOURNAL OF BIOMEDICAL SCIENCE (2009)
Identification of a Residue in Hepatitis C Virus E2 Glycoprotein That Determines Scavenger Receptor BI and CD81 Receptor Dependency and Sensitivity to Neutralizing Antibodies
Joe Grove et al.
JOURNAL OF VIROLOGY (2008)
Definition of a conserved immunodominant domain on hepatitis C virus E2 glycoprotein by neutralizing human monoclonal antibodies
Zhen-Yong Keck et al.
JOURNAL OF VIROLOGY (2008)
NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly
Yinghong Ma et al.
JOURNAL OF VIROLOGY (2008)
Induction of broad CD4+ and CD8+ T-cell responses and cross-neutralizing antibodies against hepatitis C virus by vaccination with Th1-adjuvanted polypeptides followed by defective alphaviral particles expressing envelope glycoproteins gpE1 and gpE2 and nonstructural proteins 3, 4, and 5
Yinling Lin et al.
JOURNAL OF VIROLOGY (2008)
The tight junction proteins claudin-1,-6, and-9 are entry cofactors for hepatitis C virus
Laurent Meertens et al.
JOURNAL OF VIROLOGY (2008)
Efficient trans-encapsidation of hepatitis C virus RNAs into infectious virus-like particles
Eike Steinmann et al.
JOURNAL OF VIROLOGY (2008)
A point mutation leading to hepatitis C virus escape from neutralization by a monoclonal antibody to a conserved conformational epitope
Zhen-Yong Keck et al.
JOURNAL OF VIROLOGY (2008)
Mutations in E2-PePHD, NS5A-PKRBD, NS5A-ISDR, and NS5A-V3 of hepatitis C virus genotype 1 and their relationships to pegylated interferon-ribavirin treatment responses
P. Munoz de Rueda et al.
JOURNAL OF VIROLOGY (2008)
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing
Jesus F. Salazar-Gonzalez et al.
JOURNAL OF VIROLOGY (2008)
Molecular architecture of native HIV-1 gp120 trimers
Jun Liu et al.
NATURE (2008)
In vitro selection of a neutralization-resistant hepatitis C virus escape mutant
Meital Gal-Tanamy et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Hepatitis C virus envelope glycoprotein co-evolutionary dynamics during chronic hepatitis C
Hui Li et al.
VIROLOGY (2008)
Dissecting the role of putative CD81 binding regions of E2 in mediating HCV entry: Putative CD81 binding region 1 is not involved in CD81 binding
Katharina B. Rothwang et al.
VIROLOGY JOURNAL (2008)
Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly
Nicole Appel et al.
PLOS PATHOGENS (2008)
Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion
Pablo Gastaminza et al.
JOURNAL OF VIROLOGY (2008)
Antibody-dependent enhancement of hepatitis C virus infection
Keith Meyer et al.
JOURNAL OF VIROLOGY (2008)
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge
Mansun Law et al.
NATURE MEDICINE (2008)
Identification of a broadly cross-reacting and neutralizing human monoclonal antibody directed against the hepatitis C virus E2 protein
Mario Perotti et al.
JOURNAL OF VIROLOGY (2008)
Isolation and characterization of broadly neutralizing human monoclonal antibodies to the E1 glycoprotein of hepatitis C virus
Jean-Christophe Meunier et al.
JOURNAL OF VIROLOGY (2008)
Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies
Jennifer M. Timpe et al.
HEPATOLOGY (2008)
Human apolipoprotein E is required for infectivity and production of hepatitis C virus in cell culture
Kyung-Soo Chang et al.
JOURNAL OF VIROLOGY (2007)
Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies
Zania Stamataki et al.
VACCINE (2007)
The exchangeable apolipoprotein ApoC-I promotes membrane fusion of hepatitis C virus
Marlene Dreux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Claudin-6 and claudin-9 function as additional coreceptors for hepatitis C virus
Aihua Zheng et al.
JOURNAL OF VIROLOGY (2007)
Determination of the human antibody response to the epitope defined by the hepatitis C virusneutralizing monoclonal antibody AP33
Alexander W. Tarr et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Viral sequence evolution in acute hepatitis C virus infection
Thomas Kuntzen et al.
JOURNAL OF VIROLOGY (2007)
Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus
Daniel X. Johansson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
Christopher T. Jones et al.
JOURNAL OF VIROLOGY (2007)
The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein
Francois Helle et al.
JOURNAL OF VIROLOGY (2007)
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions
Eike Steinmann et al.
PLOS PATHOGENS (2007)
Immunogenicity of papaya mosaic virus-like particles fused to a hepatitis C virus epitope: Evidence for the critical function of multimerization
Jerome Denis et al.
VIROLOGY (2007)
Hepatitis C virus epitope-specific neutralizing antibodies in Igs prepared from human plasma
Pei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees
Gamal A. Elmowalid et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Epidemiology of hepatitis C virus infection
Miriam J. Alter
WORLD JOURNAL OF GASTROENTEROLOGY (2007)
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
Matthew J. Evans et al.
NATURE (2007)
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins
Hua Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C
Jan M. Pestka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Mutagenesis of a conserved fusion peptide-like motif and membrane-proximal heptad-repeat region of hepatitis C virus glycoprotein E1
Heidi E. Drummer et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Transmembrane domains of hepatitis C virus envelope glycoproteins:: Residues involved in E1E2 heterodimerization and involvement of these domains in virus entry
Yann Ciczora et al.
JOURNAL OF VIROLOGY (2007)
Cross-genotype characterization of genetic diversity and molecular adaptation in hepatitis C virus envelope glycoprotein genes
Richard J. P. Brown et al.
JOURNAL OF GENERAL VIROLOGY (2007)
Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo
Thomas Von Hahn et al.
GASTROENTEROLOGY (2007)
Hepatitis C virus and alanine aminotransferase kinetics following B-lymphocyte depletion with rituximab: evidence for a significant role of humoral immunity in the control of viremia in chronic HCV liver disease
Gerond Lake-Bakaar et al.
BLOOD (2007)
Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus
MinKyung Yi et al.
JOURNAL OF VIROLOGY (2007)
Immunogenic and functional organization of hepatitis C virus (HCV) glycoprotein E2 on infectious HCV virions
Zhen-Yong Keck et al.
JOURNAL OF VIROLOGY (2007)
Hepatitis C virus entry requires a critical postinternalization step and delivery to early endosomes via clathrin-coated vesicles
Laurent Meertens et al.
JOURNAL OF VIROLOGY (2006)
Persistent hepatitis C virus infection in vitro: Coevolution of virus and host
Jin Zhong et al.
JOURNAL OF VIROLOGY (2006)
Diverse CD81 proteins support hepatitis C virus infection
Mike Flint et al.
JOURNAL OF VIROLOGY (2006)
Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding
Ania M. Owsianka et al.
JOURNAL OF VIROLOGY (2006)
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans
Francois Helle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Monoclonal antibody HCV-AbXTL68 in patients undergoing liver transplantation for HCV:: Results of a phase 2 randomized study
Thomas D. Schiano et al.
LIVER TRANSPLANTATION (2006)
High-density lipoproteins reduce the neutralizing effect of hepatitis C virus (HCV)-infected patient antibodies by promoting HCV entry
Cecile Voisset et al.
JOURNAL OF GENERAL VIROLOGY (2006)
A conserved Gly436-Trp-Leu-Ala-Gly-Leu-Phe-Tyr motif in hepatitis C virus glycoprotein E2 is a determinant of CD81 binding and viral entry
Heidi E. Drummer et al.
JOURNAL OF VIROLOGY (2006)
High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI
Marlene Dreux et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Hepatitis C virus entry depends on clathrin-mediated endocytosis
Emmanuelle Blanchard et al.
JOURNAL OF VIROLOGY (2006)
Mutations in carboxy-terminal part of E2 including PKR/eIF2α phosphorylation homology domain and interferon sensitivity determining region of nonstructural 5A of hepatitis C virus 1b:: Their correlation with response to interferon monotherapy and viral load
Koji Ukai et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2006)
Distribution and three-dimensional structure of AIDS virus envelope spikes
Ping Zhu et al.
NATURE (2006)
Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses
George Koutsoudakis et al.
JOURNAL OF VIROLOGY (2006)
Evolution of hepatitis C viral quasispecies and hepatic injury in perinatally infected children followed prospectively
Patrizia Farci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33
AW Tarr et al.
HEPATOLOGY (2006)
Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients
SU Nielsen et al.
JOURNAL OF VIROLOGY (2006)
Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry
DM Tscherne et al.
JOURNAL OF VIROLOGY (2006)
The interaction of natural hepatitis C virus with human scavenger receptor SR-BI/Cla1 is mediated by ApoB-containing lipoproteins
Patrick Maillard et al.
FASEB JOURNAL (2006)
Assembly of functional hepatitis C virus glycoproteins on infectious pseudoparticles occurs intracellularly and requires concomitant incorporation of E1 and E2 glycoproteins
V Sandrin et al.
JOURNAL OF GENERAL VIROLOGY (2005)
Basic residues in hyervariable region 1 of hepatitis C virus envelope glycoprotein E2 contribute to virus entry
N Callens et al.
JOURNAL OF VIROLOGY (2005)
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
P Simmonds et al.
HEPATOLOGY (2005)
Contribution of the charged residues of hepatitis C virus glycoprotein E2 transmembrane domain to the functions of the E1E2 heterodimer
Y Ciczora et al.
JOURNAL OF GENERAL VIROLOGY (2005)
Prospects for a vaccine against the hepatitis C virus
M Houghton et al.
NATURE (2005)
A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients
GL Davis et al.
LIVER TRANSPLANTATION (2005)
Complete replication of hepatitis C virus in cell culture
BD Lindenbach et al.
SCIENCE (2005)
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
T Wakita et al.
NATURE MEDICINE (2005)
An interplay between hypervariable region 1 of the Hepatitis C Virus E2 glycoprotein, the scavenger receptor BI, and high-density lipoprotein promotes both enhancement of infection and protection against neutralizing antibodies
B Bartosch et al.
JOURNAL OF VIROLOGY (2005)
Role of N-linked glycans in the functions of hepatitis C virus envelope glycoproteins
A Goffard et al.
JOURNAL OF VIROLOGY (2005)
Evolutionary dynamics of hepatitis C virus envelope genes during chronic infection
RJP Brown et al.
JOURNAL OF GENERAL VIROLOGY (2005)
Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection
D Lavillette et al.
JOURNAL OF VIROLOGY (2005)
Wide range of quasispecies diversity during primary hepatitis C virus infection
BL Herring et al.
JOURNAL OF VIROLOGY (2005)
Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1
JC Meunier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
HyPhy: hypothesis testing using phylogenies
SLK Pond et al.
BIOINFORMATICS (2005)
Folding and dimerization of hepatitis C virus E1 and E2 glycoproteins in stably transfected CHO cells
M Brazzoli et al.
VIROLOGY (2005)
Characterization of host-range and cell entry properties of the major genotypes and subtypes of hepatitis C virus
D Lavillette et al.
HEPATOLOGY (2005)
Global epidemiology of hepatitis C virus infection
CW Shepard et al.
LANCET INFECTIOUS DISEASES (2005)
Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein
A Owsianka et al.
JOURNAL OF VIROLOGY (2005)
High-resolution phylogenetic analysis of hepatitis C virus adaptation and its relationship to disease progression
I Sheridan et al.
JOURNAL OF VIROLOGY (2004)
Structure of the dengue virus envelope protein after membrane fusion
Y Modis et al.
NATURE (2004)
Cross-reactive pseudovirus-neutralizing anti-envelope antibodies coexist with antibodies devoid of such activity in persistent hepatitis C virus infection
R Burioni et al.
VIROLOGY (2004)
Long-term persistence of infection in chimpanzees inoculated with an infectious hepatitis C virus clone is associated with a decrease in the viral amino acid substitution rate and low levels of heterogeneity
J Fernandez et al.
JOURNAL OF VIROLOGY (2004)
A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers
G Leroux-Roels et al.
VACCINE (2004)
Neutralizing antibody response during acute and chronic hepatitis C virus infection
C Logvinoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Human monoclonal antibody to hepatitis C virus El glycoprotein that blocks virus attachment and viral infectivity
ZY Keck et al.
JOURNAL OF VIROLOGY (2004)
Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates
SH Jeong et al.
JOURNAL OF VIROLOGY (2004)
Genetic diversity and evolution of hepatitis C virus - 15 years on
P Simmonds
JOURNAL OF GENERAL VIROLOGY (2004)
In vitro assay for neutralizing antibody to hepatitis C virus:: Evidence for broadly conserved neutralization epitopes
B Bartosch et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate
H Barth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
M Hsu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
A ligand-binding pocket in the dengue virus envelope glycoprotein
Y Modis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes
B Bartosch et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
ConSurf: Identification of Functional Regions in Proteins by Surface-Mapping of Phylogenetic Information
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BIOINFORMATICS (2003)
Hepatitis C virus-like particles combined with novel adjuvant systems enhance virus-specific immune responses
M Qiao et al.
HEPATOLOGY (2003)
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus
E Scarselli et al.
EMBO JOURNAL (2002)
Analysis of antigenicity and topology of E2 glycoprotein present on recombinant hepatitis C virus-like particles
RF Clayton et al.
JOURNAL OF VIROLOGY (2002)
Characterization of low- and very-low-density hepatitis C virus RNA-containing particles
P André et al.
JOURNAL OF VIROLOGY (2002)
Hepatitis C virus evolutionary patterns studied through analysis of full-genome sequences
M Salemi et al.
JOURNAL OF MOLECULAR EVOLUTION (2002)
Hypervariable region 1 of hepatitis C virus: immunological decoy or biologically relevant domain?
MU Mondelli et al.
ANTIVIRAL RESEARCH (2001)
Folding of hepatitis C virus E1 glycoprotein in a cell-free system
M Merola et al.
JOURNAL OF VIROLOGY (2001)
Mapping B-cell epitopes of hepatitis C virus E2 glycoprotein using human monoclonal antibodies from phage display libraries
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JOURNAL OF VIROLOGY (2001)
Coexpression of hepatitis C virus envelope proteins E1 and E2 in cis improves the stability of membrane insertion of E2
L Cocquerel et al.
JOURNAL OF GENERAL VIROLOGY (2001)
The epidemic behavior of the hepatitis C virus
OG Pybus et al.
SCIENCE (2001)
Hepatitis C virus envelope protein E2 does not inhibit PKR by simple competition with autophosphorylation sites in the RNA-binding domain
DR Taylor et al.
JOURNAL OF VIROLOGY (2001)
Mutations in the E2-PePHD and NS5A region of hepatitis C virus type 1 and the dynamics of hepatitis C viremia decline during interferon alfa treatment
T Berg et al.
HEPATOLOGY (2000)
Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees
X Forns et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes
KG Hadlock et al.
JOURNAL OF VIROLOGY (2000)
The transmembrane domains of hepatitis C virus envelope glycoproteins E1 and E2 play a major role in heterodimerization
AO De Beeck et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV
X Forns et al.
HEPATOLOGY (2000)
The protein kinase-interacting domain in the hepatitis C virus envelope glycoprotein-2 gene is highly conserved in genotype 1-infected patients treated with interferon
SJ Polyak et al.
JOURNAL OF INFECTIOUS DISEASES (2000)
The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
P Farci et al.
SCIENCE (2000)
Charged residues in the transmembrane domains of hepatitis C virus glycoproteins play a major role in the processing, subcellular localization, and assembly of these envelope proteins
L Cocquerel et al.
JOURNAL OF VIROLOGY (2000)
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