Related references
Note: Only part of the references are listed.CD44-mediated elongated T cell spreading requires Pyk2 activation by Src family kinases, extracellular calcium, phospholipase C and phosphatidylinositol-3 kinase
Nelson K. Y. Wong et al.
CELLULAR SIGNALLING (2011)
Calpain-mediated Proteolysis of Paxillin Negatively Regulates Focal Adhesion Dynamics and Cell Migration
Christa L. Cortesio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Paxillin Associates with the Microtubule Cytoskeleton and the Immunological Synapse of CTL through Its Leucine-Aspartic Acid Domains and Contributes to Microtubule Organizing Center Reorientation
Leslie K. Robertson et al.
JOURNAL OF IMMUNOLOGY (2011)
Central role of paxillin phosphorylation in regulation of LFA-1 integrins activity and lymphocyte migration
Larisa Y. Romanova et al.
CELL ADHESION & MIGRATION (2011)
Involvement of tyrosine phosphatase CD45 in apoptosis
Genevieve Dupere-Minier et al.
APOPTOSIS (2010)
Modulation of immune cell signalling by the leukocyte common tyrosine phosphatase, CD45
A. E. Saunders et al.
CELLULAR SIGNALLING (2010)
CD45 regulates thymocyte survival during development in fetal thymic organ culture
Bindi V. Ferguson et al.
IMMUNOBIOLOGY (2010)
Crystal structures of free and ligand-bound focal adhesion targeting domain of Pyk2
James Lulo et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates
Pablo Pelegrin et al.
EMBO JOURNAL (2009)
Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design
Seungil Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Structurally distinct Phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling
Jing W. Zhu et al.
IMMUNITY (2008)
CD45 Down-Regulates Lck-Mediated CD44 Signaling and Modulates Actin Rearrangement in T Cells
Nelson K. Y. Wong et al.
JOURNAL OF IMMUNOLOGY (2008)
Collagen-mediated survival signaling is modulated by CD45 in Jurkat T cells
Krikor Bijian et al.
MOLECULAR IMMUNOLOGY (2007)
Granulocyte-macrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: Implications for CSF blockade in inflammation
Andrew J. Fleetwood et al.
JOURNAL OF IMMUNOLOGY (2007)
CpG DNA enhances macrophage cell spreading by promoting the Src-family kinase-mediated phosphorylation of paxillin
Adrian Achuthan et al.
CELLULAR SIGNALLING (2006)
The role of the α4 integrin-paxillin interaction in regulating leukocyte trafficking
David M. Rose
EXPERIMENTAL AND MOLECULAR MEDICINE (2006)
Inhibition of calpain stabilises podosomes and impairs dendritic cell motility
Yolanda Calle et al.
JOURNAL OF CELL SCIENCE (2006)
Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production
DGT Hesslein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Calpain is required for normal osteoclast function and is down-regulated by calcitonin
M Marzia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
A role for phosphatidylinositol 3-kinase in TCR-stimulated ERK activation leading to paxillin phosphorylation and CTL degranulation
LK Robertson et al.
JOURNAL OF IMMUNOLOGY (2005)
CD45 signals outside of lipid rafts to promote ERK activation, synaptic raft clustering, and IL-2 production
M Zhang et al.
JOURNAL OF IMMUNOLOGY (2005)
Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function
HL Ostergaard et al.
IMMUNOLOGIC RESEARCH (2005)
Calpain-mediated proteolysis of talin regulates adhesion dynamics
SJ Franco et al.
NATURE CELL BIOLOGY (2004)
RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner
SY Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive
LY Romanova et al.
JOURNAL OF CELL SCIENCE (2004)
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration
M Okigaki et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45
AZ Fernandis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death
XL Liu et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Calpain
BJ Perrin et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes
KO Chay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
The paxillin LD motifs
DA Tumbarello et al.
FEBS LETTERS (2002)
v-Src-induced modulation of the calpain-calpastatin proteolytic system regulates transformation
NO Carragher et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Degradation of focal adhesion proteins paxillin and p130cas by caspases or calpains in apoptotic Rat-1 and L929 cells
SR Shim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45
RH Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
CD45 negatively regulates monocytic cell differentiation by inhibiting phorbol 12-myristate 13-acetate-dependent activation and tyrosine phosphorylation of protein kinase Cδ
EL Deszo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Cleavage of focal adhesion kinase by different proteases during Src-reguIated transformation and apoptosis - Distinct roles for calpain and caspases
NO Carragher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45
M Ogimoto et al.
FEBS LETTERS (2001)
The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function
DR Alexander
SEMINARS IN IMMUNOLOGY (2000)
Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells
V Petit et al.
JOURNAL OF CELL BIOLOGY (2000)
RAFTK/Pyk2-mediated cellular signalling
H Avraham et al.
CELLULAR SIGNALLING (2000)