Related references
Note: Only part of the references are listed.The relationship between GPR40 and lipotoxicity of the pancreatic β-cells as well as the effect of pioglitazone
Peiwen Wu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Cholesterol efflux via ATP-binding cassette transporter A1 (ABCA1) and cholesterol uptake via the LDL receptor influences cholesterol-induced impairment of beta cell function in mice
J. K. Kruit et al.
DIABETOLOGIA (2010)
Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor
Delphine Gras et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Inhibition of human insulin gene transcription by peroxisome proliferator-activated receptor γ and thiazolidinedione oral antidiabetic drugs
S. Schinner et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Overexpression of GPR40 in Pancreatic β-Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice
Kae Nagasumi et al.
DIABETES (2009)
Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the KATP channel and insulin secretion in rats
T. -J. Chang et al.
DIABETOLOGIA (2009)
Peroxisome Proliferator-Activated Receptor γ Activation Restores Islet Function in Diabetic Mice through Reduction of Endoplasmic Reticulum Stress and Maintenance of Euchromatin Structure
Carmella Evans-Molina et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Rosiglitazone stimulates the release and synthesis of insulin by enhancing GLUT-2, glucokinase and BETA2/NeuroD expression
Hyo-Sup Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Lack of FFAR1/GPR40 Does Not Protect Mice From High-Fat Diet-Induced Metabolic Disease
Hong Lan et al.
DIABETES (2008)
Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion
Sara Edfalk et al.
DIABETES (2008)
In Vivo and in Vitro Studies of a Functional Peroxisome Proliferator-activated Receptor γ Response Element in the Mouse pdx-1 Promoter
Dhananjay Gupta et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Loss-of-function mutation of the GPR40 gene associates with abnormal stimulated insulin secretion by acting on intracellular calcium mobilization
Roberto Vettor et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Activation of ATP-sensitive potassium channels in rat pancreatic beta-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway
Yu-Feng Zhao et al.
JOURNAL OF ENDOCRINOLOGY (2008)
Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic β cells
Reut Bartoov-Shifman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Troglitazone acutely activates AMP-activated protein kinase and inhibits insulin secretion from beta cells
Xiao Wang et al.
LIFE SCIENCES (2007)
GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo
Martin G. Latour et al.
DIABETES (2007)
β-cell ABCA1 influences insulin secretion, glucose homeostasis and response to thiazolidinedione treatment
Liam R. Brunham et al.
NATURE MEDICINE (2007)
Free fatty acids increase cytosolic free calcium and stimulate insulin secretion from β-cells through activation of GPR40
Susanne Schnell et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2007)
Peroxisonte proliferator-activated receptor-gamma regulates expression of PDX-1 and NKX6.1 in INS-1 cells
Jacob A. Moibi et al.
DIABETES (2007)
Activation of peroxisome proliferator-activated receptor-gamma protects pancreatic beta-cells from cytokine-induced cytotoxicity via NF kappa B pathway
Eun-Kyung Kim et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
Steven E. Kahn et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Expression of the gene for a membrane-bound fatty acid receptor in the pancreas and islet cell tumours in humans: evidence for GPR40 expression in pancreatic beta cells and implications for insulin secretion
T Tomita et al.
DIABETOLOGIA (2006)
Effects of rosiglitazone and metformin on pancreatic beta cell gene expression
H Richardson et al.
DIABETOLOGIA (2006)
PPARγ and human metabolic disease
RK Semple et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Reduction in voltage-gated K+ currents in primary cultured rat pancreatic β-cells by linoleic acids
DD Feng et al.
ENDOCRINOLOGY (2006)
Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone protects human islet cells against human islet amyloid polypeptide toxicity by a phosphatidylinositol 3′-kinase-dependent pathway
CY Lin et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2005)
Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet β-cells:: mediation by PLC and L-type Ca2+ channel and link to insulin release
K Fujiwara et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Peroxisome proliferator-activated receptor α (PPARα) potentiates, whereas PPARγ attenuates, glucose-stimulated insulin secretion in pancreatic β-cells
K Ravnskjaer et al.
ENDOCRINOLOGY (2005)
Receptor-independent actions of PPAR thiazolidinedione agonists: Is mitochondrial function the key?
DL Feinstein et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet antyloid deposition in mice expressing the gene for human islet antyloid polypeptide
RL Hull et al.
DIABETES (2005)
The FFA receptor GPR40 links hyperinsulinemia, hepatic steatosis, and impaired glucose homeostasis in mouse
R Steneberg et al.
CELL METABOLISM (2005)
The biology of peroxisome proliferator -: Activated receptors -: Relationship with lipid metabolism and insulin sensitivity
P Ferré
DIABETES (2004)
Effect of PPAR-γ activation and inhibition on glucose-stimulated insulin release in INS-1e cells
E Santini et al.
DIABETES (2004)
PPAR-γ overexpression selectively suppresses insulin secretory capacity in isolated pancreatic islets through induction of UCP-2 protein
E Ito et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Pioglitazone reduces islet triglyceride content and restores impaired glucose-stimulated insulin secretion in heterozygous peroxisome proliferator-activated receptor-γ-deficient mice on a high-fat diet
J Matsui et al.
DIABETES (2004)
Convergence of peroxisome proliferator-activated receptor γ and Foxo1 signaling pathways
P Dowell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Insulin-sparing effects of troglitazone in rat pancreatic islets
LC Bollheimer et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2003)
PPAR-γ overexpression suppresses glucose-induced proinsulin biosynthesis and insulin release synergistically with pioglitazone in MIN6 cells
Y Nakamichi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids
CP Briscoe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40
Y Itoh et al.
NATURE (2003)
A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs
K Kotarsky et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)
The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic β cell growth
T Kitamura et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Glucose-induced β cell production of IL-1β contributes to glucotoxicity in human pancreatic islets
K Maedler et al.
JOURNAL OF CLINICAL INVESTIGATION (2002)
Peroxisomal proliferator-activated receptor-gamma upregulates glucokinase gene expression in beta-cells
HI Kim et al.
DIABETES (2002)
Rosiglitazone (BRL 49653) enhances insulin secretory response via phosphatidylinositol 3-kinase pathway
C Yang et al.
DIABETES (2001)
Lipotoxicity of β-cells in obesity and in other causes of fatty acid spillover
RH Unger et al.
DIABETES (2001)
Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter
H Kim et al.
DIABETES (2000)
Share Paper
