Related references
Note: Only part of the references are listed.Development and therapeutic impact of HDAC6-selective inhibitors
Sabrina Dallavalle et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Identification of an AAA ATPase VPS4B-Dependent Pathway That Modulates Epidermal Growth Factor Receptor Abundance and Signaling during Hypoxia
H. Helen Lin et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Targeting hypoxic tumour cells to overcome metastasis
Kevin L. Bennewith et al.
BMC CANCER (2011)
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
David Kaluza et al.
EMBO JOURNAL (2011)
HDAC6 is required for invadopodia activity and invasion by breast tumor cells
Mercedes Rey et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2011)
Protein kinase CK2 regulates the formation and clearance of aggresomes in response to stress
Masahiko Watabe et al.
JOURNAL OF CELL SCIENCE (2011)
cGMP Inhibits TGF-β Signaling by Sequestering Smad3 with Cytosolic β2-Tubulin in Pulmonary Artery Smooth Muscle Cells
Kaizheng Gong et al.
MOLECULAR ENDOCRINOLOGY (2011)
Opposite functions of HIF-α isoforms in VEGF induction by TGF-β1 under non-hypoxic conditions
K. S. Chae et al.
ONCOGENE (2011)
Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)
Fabrice Lucien et al.
PLOS ONE (2011)
Interdependence of HIF-1α and TGF-β/Smad3 signaling in normoxic and hypoxic renal epithelial cell collagen expression
Rajit K. Basu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2011)
Epidermal growth factor-dependent enhancement of invasiveness of squamous cell carcinoma of the breast
Fuyo Kimura et al.
CANCER SCIENCE (2010)
HIF-2α-mediated activation of the epidermal growth factor receptor potentiates head and neck cancer cell migration in response to hypoxia
Xin Wang et al.
CARCINOGENESIS (2010)
Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells
Maxime Sasseville et al.
JOURNAL OF CELL SCIENCE (2010)
Hypoxia-induced Activation of Epidermal Growth Factor Receptor (EGFR) Kinase in the Cerebral Cortex of Newborn Piglets: The Role of Nitric Oxide
Om Prakash Mishra et al.
NEUROCHEMICAL RESEARCH (2010)
Effect of EGF-Induced HDAC6 Activation on Corneal Epithelial Wound Healing
Jie Wang et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
Diaphanous-Related Formins Are Required for Invadopodia Formation and Invasion of Breast Tumor Cells
Floria Lizarraga et al.
CANCER RESEARCH (2009)
TGFβ-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels
Patricia Rottiers et al.
JOURNAL OF CELL SCIENCE (2009)
N-WASP and Cortactin Are Involved In Invadopodium-Dependent Chemotaxis to EGF In Breast Tumor Cells
Vera DesMarais et al.
CELL MOTILITY AND THE CYTOSKELETON (2009)
The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis
Yi-Shan Lee et al.
CANCER RESEARCH (2008)
Role of acetylation and extracellular location of heat shock protein 90α in tumor cell invasion
Yonghua Yang et al.
CANCER RESEARCH (2008)
A Phase II Trial of Vorinostat (Suberoylanilide Hydroxamic Acid) in Metastatic Breast Cancer: A California Cancer Consortium Study
Thehang H. Luu et al.
CLINICAL CANCER RESEARCH (2008)
Ubiquitin Proteasome System Stress Underlies Synergistic Killing of Ovarian Cancer Cells by Bortezomib and a Novel HDAC6 Inhibitor
Martina Bazzaro et al.
CLINICAL CANCER RESEARCH (2008)
TGF-β induces formation of F-actin cores and matrix degradation in human breast cancer cells via distinct signaling pathways
Shyamali Mandal et al.
EXPERIMENTAL CELL RESEARCH (2008)
A phase II study of vorinostat in the treatment of persistent or recurrent epithelial ovarian or primary peritoneal carcinoma: A Gynecologic Oncology Group study
Susan C. Modesitt et al.
GYNECOLOGIC ONCOLOGY (2008)
Requirement of HDAC6 for transforming growth factor-β1-induced epithelial-mesenchymal transition
Bin Shan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA
Mika Sakurai-Yageta et al.
JOURNAL OF CELL BIOLOGY (2008)
TGFβ-Smad2 signaling regulates the Cdh1-APC/SnoN pathway of axonal morphogenesis
Judith Stegmuller et al.
JOURNAL OF NEUROSCIENCE (2008)
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7
Shusheng Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion
Katarina Wolf et al.
NATURE CELL BIOLOGY (2007)
HDAC6 modulates cell motility by altering the acetylation level of cortactin
Xiaohong Zhang et al.
MOLECULAR CELL (2007)
A tale of two proteins:: Differential roles and regulation of Smad2 and Smad3 in TGF-β signaling
Kimberly A. Brown et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Hypoxia induces the activation of human hepatic stellate cells LX-2 through TGF-β signaling pathway
Yue-Feng Shi et al.
FEBS LETTERS (2007)
Histone deacetylase inhibitors in cancer treatment:: A review of the clinical toxicity and the modulation of gene expression in cancer cells
O. Bruserud et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2007)
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma, (CTCL)
Madeleine Duvic et al.
BLOOD (2007)
Actin dynamics at sites of extracellular matrix degradation
Massimiliano Baldassarre et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2006)
Phosphoinositide-3 kinase-Rac1-c-Jun NH2-terminal kinase signaling mediates collagen I-induced cell scattering and up-regulation of N-cadherin expression in mouse mammary epithelial cells
Yasushi Shintani et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Targeting histone deacetylase in cancer therapy
Hsiang-Yu Lin et al.
MEDICINAL RESEARCH REVIEWS (2006)
Hypoxia stimulates breast carcinoma cell invasion through MT1-MMP and MMP-2 activation
UM Muñoz-Nájar et al.
ONCOGENE (2006)
Dynamic interactions of cortactin and membrane type 1 matrix metalloproteinase at invadopodia: Defining the stages of invadopodia formation and function
VV Artym et al.
CANCER RESEARCH (2006)
The tumor suppressor Smad4 is required for transforming growth factor β-induced epithelial to mesenchymal transition and bone metastasis of breast cancer cells
M Deckers et al.
CANCER RESEARCH (2006)
Smad3 is key to TGF-β-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
AB Roberts et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2006)
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-β1-induced extracellular matrix expression
M Jinnin et al.
MOLECULAR PHARMACOLOGY (2006)
Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation
WJ Ju et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Role for casein kinase 2 in the regulation of HIF-1 activity
D Mottet et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors
C Bradbury et al.
LEUKEMIA (2005)
Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the α6β4 integrin
SO Yoon et al.
CANCER RESEARCH (2005)
TGF-ß and the smad signaling pathway suppor transcriptomic reprogramming during epithelial-mesenchymal cell transition
U Valcourt et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Cadherin switching: essential for behavioral but not morphological changes during an epithelium-to-mesenchyme transition
M Maeda et al.
JOURNAL OF CELL SCIENCE (2005)
Histone deacetylase inhibitors and cancer: from cell biology to the clinic
H Hess-Stumpp
EUROPEAN JOURNAL OF CELL BIOLOGY (2005)
Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1 - Impact on the bioactivation of proproteins
S McMahon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin
H Yamaguchi et al.
JOURNAL OF CELL BIOLOGY (2005)
Transforming growth factor β-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation
JM Scandura et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Synthesis and activity of new aryl- and heteroaryl- substituted pyrazole inhibitors of the transforming growth factor-b type I receptor kinase domain
JS Sawyer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation
SJ Haggarty et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Cellular response to hypoxia involves signaling via Smad proteins
H Zhang et al.
BLOOD (2003)
Dynamin participates in focal extracellular matrix degradation by invasive cells
M Baldassarre et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Development of cDNA microarray for expression profiling of estrogen-responsive genes
A Inoue et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2002)
HDAC6 is a microtubule-associated deacetylase
C Hubbert et al.
NATURE (2002)
Histone deacetylases and cancer: Causes and therapies
PA Marks et al.
NATURE REVIEWS CANCER (2001)
Response to hypoxia involves transforming growth factor-β2 and Smad proteins in human endothelial cells
HO Akman et al.
BLOOD (2001)
Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor β1-induced furin gene transactivation
F Blanchette et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Evidence that furin is an authentic transforming growth factor-beta 1-converting enzyme
CM Dubois et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases
I Yana et al.
MOLECULAR BIOLOGY OF THE CELL (2000)
Microtubule binding to Smads may regulate TGF beta activity
CM Dong et al.
MOLECULAR CELL (2000)
Share Paper
