4.6 Article

Engineering of Three-Finger Fold Toxins Creates Ligands with Original Pharmacological Profiles for Muscarinic and Adrenergic Receptors

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Adrenoceptor activity of muscarinic toxins identified from mamba venoms

K. Nareoja et al.

BRITISH JOURNAL OF PHARMACOLOGY (2011)

Review Biotechnology & Applied Microbiology

Venoms as a platform for human drugs: translating toxins into therapeutics

Glenn F. King

EXPERT OPINION ON BIOLOGICAL THERAPY (2011)

Review Pharmacology & Pharmacy

Muscarinic toxins

Denis Servent et al.

TOXICON (2011)

Article Biochemical Research Methods

Molecular replacement with MOLREP

Alexei Vagin et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

Features and development of Coot

P. Emsley et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)

Article Biochemical Research Methods

PHENIX: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)

Article Pharmacology & Pharmacy

The three-finger toxin MTα is a selective α2B-adrenoceptor antagonist

Katja Koivula et al.

TOXICON (2010)

Review Biochemistry & Molecular Biology

Muscarinic toxins: tools for the study of the pharmacological and functional properties of muscarinic receptors

Denis Servent et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Biochemistry & Molecular Biology

The three-fingered protein domain of the human genome

A. Galat

CELLULAR AND MOLECULAR LIFE SCIENCES (2008)

Article Biochemistry & Molecular Biology

β-Cardiotoxin:: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity

Nandhakishore Rajagopalan et al.

FASEB JOURNAL (2007)

Article Biochemical Research Methods

The integration of macromolecular diffraction data

AGW Leslie

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)

Review Biochemistry & Molecular Biology

Diversity of folds in animal toxins acting on ion channels

S Mouhat et al.

BIOCHEMICAL JOURNAL (2004)

Article Biochemical Research Methods

Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions

E Krissinel et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Effects of muscarinic toxins MT1 and MT2 from green mamba on different muscarinic cholinoceptors

AL Harvey et al.

NEUROCHEMICAL RESEARCH (2002)

Article Pharmacology & Pharmacy

Molecular moulds with multiple missions: Functional sites in three-finger toxins

RM Kini

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2002)

Article Pharmacology & Pharmacy

Inhibition of acetylcholine muscarinic M1 receptor function by the M1-selective ligand muscarinic toxin 7 (MT-7)

MC Olianas et al.

BRITISH JOURNAL OF PHARMACOLOGY (2000)

Article Biochemistry & Molecular Biology

Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal α7-nicotinic acetylcholine receptor

S Antil-Delbeke et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Do structural deviations between toxins adopting the same fold reflect functional differences?

A Ricciardi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Chemical engineering of a three-fingered toxin with anti-alpha 7 neuronal acetylcholine receptor activity

G Mourier et al.

PROTEIN ENGINEERING (2000)