4.6 Article

Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Genetic mouse models for Parkinson's disease display severe pathology in glial cell mitochondria

Saskia Schmidt et al.

HUMAN MOLECULAR GENETICS (2011)

Article Geriatrics & Gerontology

Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation

Eugenie Mutez et al.

NEUROBIOLOGY OF AGING (2011)

Article Oncology

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity

Hye Young Heo et al.

EXPERIMENTAL CELL RESEARCH (2010)

Article Immunology

LRRK2 Is Involved in the IFN-γ Response and Host Response to Pathogens

Agnes Gardet et al.

JOURNAL OF IMMUNOLOGY (2010)

Article Biochemistry & Molecular Biology

MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2

Cindy H. Hsu et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease

Byoung Dae Lee et al.

NATURE MEDICINE (2010)

Article Genetics & Heredity

Parkinson's Disease and Low Frequency Alleles Found Together Throughout LRRK2

Coro Paisan-Ruiz et al.

ANNALS OF HUMAN GENETICS (2009)

Article Biochemistry & Molecular Biology

Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1

Jens Waak et al.

FASEB JOURNAL (2009)

Article Biochemistry & Molecular Biology

The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro

Christian Johannes Gloeckner et al.

JOURNAL OF NEUROCHEMISTRY (2009)

Article Medicine, General & Internal

Genomewide Association Study of Leprosy

Fu-Ren Zhang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Multidisciplinary Sciences

R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice

Youren Tong et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Oncology

LRRK2 regulates synaptic vesicle endocytosis

Narae Shin et al.

EXPERIMENTAL CELL RESEARCH (2008)

Article Biochemistry & Molecular Biology

Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells

Edward D. Plowey et al.

JOURNAL OF NEUROCHEMISTRY (2008)

Article Neurosciences

Glial dysfunction in parkin null mice:: Effects of aging

Rosa M. Solano et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Neurosciences

Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration

Tamy C. Frank-Cannon et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Genetics & Heredity

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Jeffrey C. Barrett et al.

NATURE GENETICS (2008)

Article Neurosciences

Wild-type LRRK2 but not its mutant attenuates stress-induced cell death via ERK pathway

Anthony K. F. Liou et al.

NEUROBIOLOGY OF DISEASE (2008)

Review Pharmacology & Pharmacy

Inflammation as a causative factor in the aetiology of Parkinson's disease

P. S. Whitton

BRITISH JOURNAL OF PHARMACOLOGY (2007)

Article Biochemistry & Molecular Biology

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila

Sung Bae Lee et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Neurosciences

MAPK-pathway activity, Lrrk2 G2019S, and Parkinson's disease

Linda R. White et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2007)

Article Biochemistry & Molecular Biology

Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity

Andrew B. West et al.

HUMAN MOLECULAR GENETICS (2007)

Article Neurosciences

Kinase activity of mutant LRRK2 mediates neuronal toxicity

Wanli W. Smith et al.

NATURE NEUROSCIENCE (2006)

Article Clinical Neurology

LRRK2 expression in normal and pathologic human brain and in human cell lines

Judith Miklossy et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)

Review Immunology

The many paths to p38 mitogen-activated protein kinase activation in the immune system

Jonathan D. Ashwell

NATURE REVIEWS IMMUNOLOGY (2006)

Review Cell Biology

Signaling to NF-κB

MS Hayden et al.

GENES & DEVELOPMENT (2004)

Article Biochemistry & Molecular Biology

Phosphorylation of serine 337 of NF-κB p50 is critical for DNA binding

SH Hou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Role of nitric oxide in rotenone-induced nigro-striatal injury

Y He et al.

JOURNAL OF NEUROCHEMISTRY (2003)

Article Immunology

Prothrombin kringle-2 activates cultured rat brain microglia

J Ryu et al.

JOURNAL OF IMMUNOLOGY (2002)

Article Biochemistry & Molecular Biology

Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-κB

J Ryu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)