4.6 Article

Metformin Treatment Has No Beneficial Effect in a Dose-Response Survival Study in the SOD1G93A Mouse Model of ALS and Is Harmful in Female Mice

Related references

Note: Only part of the references are listed.
Editorial Material Endocrinology & Metabolism

New aspects of an old drug: metformin as a glucagon-like peptide 1 (GLP-1) enhancer and sensitiser

Y. M. Cho et al.

DIABETOLOGIA (2011)

Article Biochemistry & Molecular Biology

The Dying-Back Phenomenon of Motor Neurons in ALS

Michal Dadon-Nachum et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2011)

Review Clinical Neurology

Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis

L. M. Duffy et al.

NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2011)

Article Clinical Neurology

Guidelines for preclinical animal research in ALS/MND: A consensus meeting

Albert C. Ludolph et al.

AMYOTROPHIC LATERAL SCLEROSIS (2010)

Article Clinical Neurology

ALS disease onset may occur later in patients with pre-morbid diabetes mellitus

A. Jawaid et al.

EUROPEAN JOURNAL OF NEUROLOGY (2010)

Review Neurosciences

Inflammation in ALS and SMA: Sorting out the good from the evil

Dimitra Papadimitriou et al.

NEUROBIOLOGY OF DISEASE (2010)

Article Endocrinology & Metabolism

Metformin Inhibits Aromatase via an Extracellular Signal-Regulated Kinase-Mediated Pathway

Suman Rice et al.

ENDOCRINOLOGY (2009)

Review Cell Biology

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

Hristelina Ilieva et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription

Yaomin Chen et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Clinical Neurology

Review: Evidence-based drug treatment in amyotrophic lateral sclerosis and upcoming clinical trials

Albert C. Ludolph et al.

Therapeutic Advances in Neurological Disorders (2009)

Article Clinical Neurology

Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis

Wade S. Parkhouse et al.

AMYOTROPHIC LATERAL SCLEROSIS (2008)

Review Clinical Neurology

Design, power, and interpretation of studies in the standard murine model of ALS

Sean Scott et al.

AMYOTROPHIC LATERAL SCLEROSIS (2008)

Review Biochemistry & Molecular Biology

Amyotrophic lateral sclerosis: From current developments in the laboratory to clinical implications

Mauro Cozzolino et al.

ANTIOXIDANTS & REDOX SIGNALING (2008)

Article Clinical Neurology

Effects of estrogen on lifespan and motor functions in female hSOD1 G93A transgenic mice

Chan-Il Choi et al.

JOURNAL OF THE NEUROLOGICAL SCIENCES (2008)

Article Clinical Neurology

Dyslipidemia is a protective factor in amyotrophic lateral sclerosis

L. Dupuis et al.

NEUROLOGY (2008)

Article Neurosciences

Metformin therapy in a transgenic mouse model of Huntington's disease

Thong C. Ma et al.

NEUROSCIENCE LETTERS (2007)

Article Multidisciplinary Sciences

Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials

Alberto Ferri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Clinical Neurology

Neuroprotective agents for clinical trials in ALS - A systematic assessment

B. J. Traynor et al.

NEUROLOGY (2006)

Article Hematology

Metformin inhibits proinflammatory responses and nuclear factor-κB in human vascular wall cells

K Isoda et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2006)

Article Endocrinology & Metabolism

Metformin decreases intracellular production of reactive oxygen species in aortic endothelial cells

N Ouslimani et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2005)

Article Neurosciences

Effect of transgene copy number on survival in the G93A SOD1 transgenic mouse model of ALS

GM Alexander et al.

MOLECULAR BRAIN RESEARCH (2004)

Article Clinical Neurology

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS

CY Zheng et al.

ANNALS OF NEUROLOGY (2004)

Review Neurosciences

Experimental therapeutics in transgenic mouse models of Huntington's disease

MF Beal et al.

NATURE REVIEWS NEUROSCIENCE (2004)

Article Obstetrics & Gynecology

Metformin has direct effects on human ovarian steroidogenesis

R Mansfield et al.

FERTILITY AND STERILITY (2003)

Article Medicine, Research & Experimental

Role of AMP-activated protein kinase in mechanism of metformin action

GC Zhou et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)

Article Biochemistry & Molecular Biology

Metformin reverses fatty liver disease in obese, leptin-deficient mice

HZ Lin et al.

NATURE MEDICINE (2000)