Related references
Note: Only part of the references are listed.Membrane Cholesterol Modulates β-Amyloid-dependent Tau Cleavage by Inducing Changes in the Membrane Content and Localization of N-Methyl-D-aspartic Acid Receptors
Alexandra M. Nicholson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cysteine Proteases Bleomycin Hydrolase and Cathepsin Z Mediate N-terminal Proteolysis and Toxicity of Mutant Huntingtin
Tamara Ratovitski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment
Sarika Garg et al.
NEUROBIOLOGY OF AGING (2011)
Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains
Sebastien Feuillette et al.
BRAIN RESEARCH (2010)
A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration
Kanae Iijima-Ando et al.
HUMAN MOLECULAR GENETICS (2010)
Calpain Activation Promotes BACE1 Expression, Amyloid Precursor Protein Processing, and Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease
Bin Liang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein
Sebastien Feuillette et al.
JOURNAL OF NEUROCHEMISTRY (2010)
The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo
Carin A. Loewen et al.
PLOS ONE (2010)
Lysosomal Dysfunction Promotes Cleavage and Neurotoxicity of Tau In Vivo
Vikram Khurana et al.
PLOS GENETICS (2010)
Increased Membrane Cholesterol Might Render Mature Hippocampal Neurons More Susceptible to β-Amyloid-Induced Calpain Activation and Tau Toxicity
Alexandra M. Nicholson et al.
JOURNAL OF NEUROSCIENCE (2009)
Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression
Mala V. Rao et al.
JOURNAL OF NEUROSCIENCE (2008)
The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons
Roxana C. Sinjoanu et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
Tau phosphorylation sites work in concert to promote neurotoxicity in vivo
Michelle L. Steinhilb et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Stepwise proteolysis liberates tau fragments that nucleate the Alzheimer-like aggregation of full-length tau in a neuronal cell model
Y. P. Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Tau aggregation and toxicity in a cell culture model of tauopathy
Bhaswati Bandyopadhyay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
S/P and T/P phosphorylation is critical for tau neurotoxicity in Drosophila
Michelle L. Steinhilb et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2007)
Substance P provides neuroprotection in cerebellar granule cells through Akt and MAPK/Erk activation: Evidence for the involvement of the delayed rectifier potassium current
G. Amadoro et al.
NEUROPHARMACOLOGY (2007)
Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila
Olivier Blard et al.
HUMAN MOLECULAR GENETICS (2007)
Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo
Tudor A. Fulga et al.
NATURE CELL BIOLOGY (2007)
Caspase-3- and calpain-mediated tau cleavage are differentially prevented by estrogen and testosterone in beta-amyloid-treated hippocampal neurons
S. -Y. Park et al.
NEUROSCIENCE (2007)
Oxidative stress mediates tau-induced neurodegeneration in Drosophila
Dora Dias-Santagata et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Huntingtin phosphorylation sites mapped by mass spectrometry - Modulation of cleavage and toxicity
Birgit Schilling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
NMDA receptor mediates tau-induced neurotoxicity by calpain and ERK/MAPK activation
G Amadoro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Inducible expression of tau repeat domain in cell models of tauopathy - Aggregation is toxic to cells but can be reversed by inhibitor drugs
I Khlistunova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Determination of peptide substrate specificity for μ-calpain by a peptide library-based approach -: The importance of promed side interactions
D Cuerrier et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer
B Dermaut et al.
JOURNAL OF CELL BIOLOGY (2005)
The generation of a 17 kDa neurotoxic fragment:: An alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration
SY Park et al.
JOURNAL OF NEUROSCIENCE (2005)
Proteasome inhibition and Tau proteolysis:: an unexpected regulation
P Delobel et al.
FEBS LETTERS (2005)
Calpain inhibitor inhibits p35-p25-Cdk5 activation, decreases Tau hyperphosphorylation, and improves neurological function after spinal cord hemisection in rats
KS Hung et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Recent Evidence Regarding a Role for Cdk5 Dysregulation in Alzheimer's Disease
E. A. Monaco
CURRENT ALZHEIMER RESEARCH (2004)
The calpain-system of Drosophila melanogaster:: coming of age
P Friedrich et al.
BIOESSAYS (2004)
DUK114, the Drosophila orthologue of bovine brain calpain activator protein, is a molecular chaperone
A Farkas et al.
BIOCHEMICAL JOURNAL (2004)
Calpain mediates calcium-induced activation of the Erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons - Relevance to Alzheimer's disease
Veeranna et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
S Oddo et al.
NEURON (2004)
Proteins released from degenerating neurons are surrogate markers for acute brain damage
R Siman et al.
NEUROBIOLOGY OF DISEASE (2004)
On the sequential determinants of calpain cleavage
P Tompa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Inhibition of calpain cleavage of huntingtin reduces toxicity - Accumulation of calpain/caspase fragments in the nucleus
J Gafni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The calpains in aging and aging-related diseases
RA Nixon
AGEING RESEARCH REVIEWS (2003)
Synthesis and evaluation of fluorescent probes for the detection of calpain activity
S Mittoo et al.
ANALYTICAL BIOCHEMISTRY (2003)
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
W Noble et al.
NEURON (2003)
P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein
E Adamec et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2002)
Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2
E Adamec et al.
ACTA NEUROPATHOLOGICA (2002)
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
JC Augustinack et al.
ACTA NEUROPATHOLOGICA (2002)
Tauopathy in Drosophila:: Neurodegeneration without neurofibrillary tangles
CW Wittmann et al.
SCIENCE (2001)
Neurotoxicity induces cleavage of p35 to p25 by calpain
MS Lee et al.
NATURE (2000)
Up-regulation of the lysosomal system in experimental models of neuronal injury: Implications for Alzheimer's disease
E Adamec et al.
NEUROSCIENCE (2000)
Share Paper
