Related references
Note: Only part of the references are listed.BH3-only Activator Proteins Bid and Bim Are Dispensable for Bak/Bax-dependent Thrombocyte Apoptosis Induced by Bcl-xL Deficiency MOLECULAR REQUISITES FOR THE MITOCHONDRIAL PATHWAY TO APOPTOSIS IN PLATELETS
Takahiro Kodama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells
A. Caro-Maldonado et al.
CELL DEATH AND DIFFERENTIATION (2010)
Targeting Mitochondria for Cancer Therapy
David M. Hockenbery
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2010)
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
Gideon Bollag et al.
NATURE (2010)
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
Cory M. Johannessen et al.
NATURE (2010)
Melanomas acquire resistance toB-RAF(V600E) inhibition by RTK or N-RAS upregulation
Ramin Nazarian et al.
NATURE (2010)
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
L. A. Pradelli et al.
ONCOGENE (2010)
BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program
Decheng Ren et al.
SCIENCE (2010)
Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1
Ryuji Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2009)
Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors
Kazuki N. Sugahara et al.
CANCER CELL (2009)
PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis
Jerry E. Chipuk et al.
CELL CYCLE (2009)
Apoptosis commitment and activation of mitochondrial Bax during anoikis is regulated by p38MAPK
T. W. Owens et al.
CELL DEATH AND DIFFERENTIATION (2009)
The Glycolytic Inhibitor 2-Deoxyglucose Activates Multiple Prosurvival Pathways through IGF1R
Diansheng Zhong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Bcl-xL increases mitochondrial fission, fusion, and biomass in neurons
Sarah B. Berman et al.
JOURNAL OF CELL BIOLOGY (2009)
Mitochondrial Outer Membrane Proteins Assist Bid in Bax-mediated Lipidic Pore Formation
Blanca Schafer et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737
Paula Hauck et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer
Marc L. Hyer et al.
CANCER RESEARCH (2008)
ABT-263: A potent and orally bioavailable Bcl-2 family inhibitor
Christin Tse et al.
CANCER RESEARCH (2008)
Therapeutic efficacy of ABT-737, a selective inhibitor of BCL-2, in small cell lung cancer
Christine L. Hann et al.
CANCER RESEARCH (2008)
Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax
Jonathan F. Lovell et al.
CELL (2008)
A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells
M. Vogler et al.
CELL DEATH AND DIFFERENTIATION (2008)
2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition
Diansheng Zhong et al.
MOLECULAR CANCER THERAPEUTICS (2008)
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
Ryuji Yamaguchi et al.
MOLECULAR CELL (2008)
Dasatinib induces durable cytogenetic responses in patients with chronic myelogenous leukemia in chronic phase with resistance or intolerance to imatinib
A. Hochhaus et al.
LEUKEMIA (2008)
Phosphorylation of the Translation Initiation Factor eIF2α Increases BACE1 Levels and Promotes Amyloidogenesis
Tracy O'Connor et al.
NEURON (2008)
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis
Sara Wojciechowski et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737
X. Lin et al.
ONCOGENE (2007)
Programmed anuclear cell death delimits platelet life span
Kylie D. Mason et al.
CELL (2007)
Combining radioimmunotherapy with antihypoxia therapy 2-deoxy-D-glucose results in reduction of therapeutic efficacy
Jason L. J. Dearling et al.
CLINICAL CANCER RESEARCH (2007)
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
Simon N. Willis et al.
SCIENCE (2007)
Mitochondrial fragmentation in apoptosis
Damien Arnoult
TRENDS IN CELL BIOLOGY (2007)
Diallyl trisulfide suppresses growth of PC-3 human prostate cancer xenograft in vivo in association with Bax and Bak induction
Dong Xiao et al.
CLINICAL CANCER RESEARCH (2006)
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
Mark F. van Delft et al.
CANCER CELL (2006)
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
Marina Konopleva et al.
CANCER CELL (2006)
Role of Bax and Bak in mitochondrial morphogenesis
Mariusz Karbowski et al.
NATURE (2006)
Endothelin receptor a blockade enhances taxane effects in prostate cancer
Ardavan Akhavan et al.
NEOPLASIA (2006)
Mechanisms of Disease: oncogene addiction - a rationale for molecular targeting in cancer therapy
I. Bernard Weinstein et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2006)
Glycolysis inhibition for anticancer treatment
H. Pelicano et al.
ONCOGENE (2006)
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
T Oltersdorf et al.
NATURE (2005)
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
SN Willis et al.
GENES & DEVELOPMENT (2005)
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
CP Baines et al.
NATURE (2005)
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
T Nakagawa et al.
NATURE (2005)
2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
G Maschek et al.
CANCER RESEARCH (2004)
Allyl isothiocyanate, a constituent of cruciferous vegetables, inhibits growth of PC-3 human prostate cancer xenografts in vivo
SK Srivastava et al.
CARCINOGENESIS (2003)
Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop
C von Haefen et al.
ONCOGENE (2003)
Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing
C Muñoz-Pinedo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571
NJ Donato et al.
BLOOD (2003)
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
T Kuwana et al.
CELL (2002)
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia.
H Kantarjian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Differential inactivation of caspase-8 in lung cancers
N Shivapurkar et al.
CANCER BIOLOGY & THERAPY (2002)
Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome.
BJ Druker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
Cellular release of [18F]2-fluoro-2-deoxyglucose as a function of the glucose-6-phosphatase enzyme system
C Caracó et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cleavage of BID during cytotoxic drug and UV radiation-induced apoptosis occurs downstream of the point of Bcl-2 action and is catalysed by caspase-3:: a potential feedback loop for amplification of apoptosis-associated mitochondrial cytochrome c release
EA Slee et al.
CELL DEATH AND DIFFERENTIATION (2000)
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
JC Goldstein et al.
NATURE CELL BIOLOGY (2000)